Recombinant Mouse Interleukin-5 protein(Il5) (Active)

In Stock
Code CSB-AP003311MO
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P04401
Lead Time 5-10 business days
Storage Buffer 0.2 m filtered 20 mM Tris, pH 9.0, 150 mM NaCl ,lyophilized
Alias IL-5, BCGF-II, Cytotoxic T-lymphocyte inducer, Eosinophil differentiation factor, T-cell replacing factor
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
Purity >98% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG
Research Area Immunology
Source E.coli
Gene Names Il5
Expression Region 21-133aa
Tag Info Tag-Free
Mol. Weight 26.2 kDa
Protein Description Full Length of Mature Protein
PubMed ID 3133208; 3024009; 3078564; 2215480
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Function Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells.
Subcellular Location Secreted
Protein Families IL-5 family
Database Links

KEGG: mmu:16191

STRING: 10090.ENSMUSP00000043369

UniGene: Mm.4461

Pathway Jak-STAT signaling pathway
Fc epsilon RI signaling pathway
Hematopoietic cell lineage
IL-17 signaling pathway
T cell receptor signaling pathway
Th1 and Th2 cell differentiation

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