TUBB3 Monoclonal Antibody

Datasheet
Code CSB-MA000185
Product Type Monoclonal Antibody
Size US$167
Uniprot No. Q13509
Image
  • IHC Staining of Human colon tissue, diluted at 1:200.

  • Western blot analysis of A549 (1), Rat brain (2), Mouse brain (3), Chicken lung (4) and Rabbit testis (5), Sheep muscle (6), diluted at 1:5000.

  • IF analysis of Hela with β-Tubulin Monoclonal Antibody(Left) and DAPI (Right) diluted at 1:100.

Immunogen Synthetic Peptide
Raised in Mouse
Species Reactivity H,R,M,Mk,Dg,Ch,Hm,Rb,Sh,Insect,Yeast
Tested Applications ELISA,WB,IHC;Recommended dilution:WB:1:500-1:5000,IHC:1:50-1:500
Form Liquid
Conjugate Non-conjugated
Storage Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Isotype IgG
Alias TUBB3; TUBB4; Tubulin beta-3 chain; Tubulin beta-4 chain; Tubulin beta-III
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Gene Names TUBB3
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. TUBB3 plays a critical role in proper axon guidance and mantainance.
Involvement in disease Fibrosis of extraocular muscles, congenital, 3A (CFEOM3A); Cortical dysplasia, complex, with other brain malformations 1 (CDCBM1)
Subcellular Location Cytoplasm, cytoskeleton
Protein Families Tubulin family
Tissue Specificity Expression is primarily restricted to central and peripheral nervous system. Greatly increased expression in most cancerous tissues.
Database Links

HGNC: 20772

OMIM: 600638

KEGG: hsa:10381

STRING: 9606.ENSP00000320295

UniGene: Hs.511743

Pathway Gap junction

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