Recombinant Human Endothelin-1(EDN1),partial

Code CSB-RP063044h
Product Type Other
Size US$1726Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P05305
Relevance Endothelins are endothelium-derived vasoconstrictor peptides.
Image
  • (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
  • Activity
    Measured by its binding ability in a functional ELISA. Immobilized EDNRB at 5 μg/ml can bind human EDN1 with a linear range of 6.25-25.00 μg/ml.
Storage Buffer Tris-based buffer,50% glycerol
Alias Preproendothelin-1 ;PPET1
Species Homo sapiens (Human)
Biological_Activity Measured by its binding ability in a functional ELISA. Immobilized EDNRB at 5 μg/ml can bind human EDN1 with a linear range of 6.25-25.00 μg/ml.
Purity Greater than 90% as determined by SDS-PAGE.
Sequence CSCSSLMDKECVYFCHLDIIW
Research Area Signal Transduction
Source E.coli
Gene Names EDN1
Expression Region 53-73aa
Tag Info N-terminal GST-tagged
Mol. Weight 29.5kDa
Protein Description partial
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.
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Function Endothelins are endothelium-derived vasoconstrictor peptides.
Involvement in disease Question mark ears, isolated (QME); Auriculocondylar syndrome 3 (ARCND3)
Subcellular Location Secreted
Protein Families Endothelin/sarafotoxin family
Tissue Specificity Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Database Links

HGNC: 3176

OMIM: 131240

KEGG: hsa:1906

STRING: 9606.ENSP00000368683

UniGene: Hs.511899

Pathway HIF-1 signaling pathway
Melanogenesis
TNF signaling pathway
AGE-RAGE signaling pathway in diabetic complications

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