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| Code | CSB-PA007400GA01HU |
| Product Type | Purified Rabbit Anti human PolyClonal Antibody |
| Size | US$685 |
| Uniprot No. | P05305 |
| Immunogen | Human EDN1 |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA,WB,IHC |
| Storage Buffer | PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method | Antigen Affinity Purified |
| Isotype | IgG |
| Alias | endothelin 1;EDN1;ET1;HDLCQ7 ; |
| Immunogen Species | Homo sapiens (Human) |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Target Names | EDN1 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Target Details | This protein is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. |
| HGNC | 3176 |
| RGD | 2532 |
| MGI | 95283 |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Endothelins are endothelium-derived vasoconstrictor peptides. |
| Involvement in disease | Question mark ears, isolated (QME); Auriculocondylar syndrome 3 (ARCND3) |
| Subcellular Location | Secreted |
| Protein Families | Endothelin/sarafotoxin family |
| Tissue Specificity | Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells. |
| Database Links |
HGNC: 3176 OMIM: 131240 KEGG: hsa:1906 STRING: 9606.ENSP00000368683 UniGene: Hs.511899 |
| Pathway |
HIF-1 signaling pathway
Melanogenesis TNF signaling pathway AGE-RAGE signaling pathway in diabetic complications |
EDN1 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004918 | EDN1 Antibody | Human | WB,ELISA |
| CSB-PA924161 | EDN1 Antibody | Human | ELISA,IHC |
| CSB-PA784177 | EDN1 Antibody | Human | ELISA,IHC |
| CSB-PA198612 | EDN1 Antibody | Human | ELISA,IHC |
EDN1 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-RP063044h | Recombinant Human Endothelin-1(EDN1),partial | E.coli |
| CSB-YP007400HU CSB-EP007400HU CSB-BP007400HU CSB-MP007400HU |
Recombinant Human Endothelin-1(EDN1),partial | Yeast E.coli Baculovirus Mammalian cell |
EDN1 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E07007h | Human Endothelin 1,ET-1 ELISA Kit | serum, cell culture supernates, urine, saliva | 0.78 pg/mL |
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