EDN1 Antibody

Datasheet
Code CSB-PA007400GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. P05305
Immunogen Human EDN1
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA,WB,IHC
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity Purified
Isotype IgG
Alias endothelin 1;EDN1;ET1;HDLCQ7 ;
Immunogen Species Homo sapiens (Human)
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Target Names EDN1
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details This protein is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene.
HGNC 3176
RGD 2532
MGI 95283
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Function Endothelins are endothelium-derived vasoconstrictor peptides.
Involvement in disease Question mark ears, isolated (QME); Auriculocondylar syndrome 3 (ARCND3)
Subcellular Location Secreted
Protein Families Endothelin/sarafotoxin family
Tissue Specificity Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Database Links

HGNC: 3176

OMIM: 131240

KEGG: hsa:1906

STRING: 9606.ENSP00000368683

UniGene: Hs.511899

Pathway HIF-1 signaling pathway
Melanogenesis
TNF signaling pathway
AGE-RAGE signaling pathway in diabetic complications

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