ADCY4 Antibody

Code CSB-PA249707
Size US$166
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Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA249707(ADCY4 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA249707(ADCY4 Antibody) at dilution 1/45, on the right is treated with fusion protein. (Original magnification: ×200)
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Product Details

Uniprot No.
Target Names
ADCY4
Alternative Names
AC4 antibody; Adcy4 antibody; ADCY4_HUMAN antibody; Adenylate cyclase 4 antibody; Adenylate cyclase type 4 antibody; Adenylate cyclase type IV antibody; Adenylyl cyclase 4 antibody; Adenylyl cyclase antibody; ATP pyrophosphate lyase 4 antibody; ATP pyrophosphate lyase antibody; ATP pyrophosphate-lyase 4 antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Fusion protein of Human ADCY4
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Isotype
IgG
Purification Method
Antigen affinity purification
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Form
Liquid
Tested Applications
ELISA,IHC
Recommended Dilution
Application Recommended Dilution
ELISA 1:2000-1:5000
IHC 1:50-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
Gene References into Functions
  1. AC4 and AC2, both isoforms stimulated by Gbetagamma, are expressed in bronchial nonlipid raft membrane fractions where they colocalize with and couple to prostanoid EP2 receptors. PMID: 21228062
  2. This paper reports the presence of adenylyl cyclases 2, 3, and 4 in mouse olfactory cilia. PMID: 11055432
  3. The HIV-1 regulatory protein Tat was shown to inhibit the activity of adenylyl cyclase in rat microglial cells. PMID: 11299302
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein Families
Adenylyl cyclase class-4/guanylyl cyclase family
Tissue Specificity
Detected in the zona glomerulosa and the zona fasciculata in the adrenal gland (at protein level).
Database Links

HGNC: 235

OMIM: 600292

KEGG: hsa:196883

STRING: 9606.ENSP00000312126

UniGene: Hs.443428

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