ADCY4 Antibody

Code CSB-PA822782ESR2HU
Size US$166
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  • Immunohistochemistry of paraffin-embedded human thyroid tissue using CSB-PA822782ESR2HU at dilution of 1:100

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Product Details

Full Product Name
Rabbit anti-Homo sapiens (Human) ADCY4 Polyclonal antibody
Uniprot No.
Target Names
ADCY4
Alternative Names
AC4 antibody; Adcy4 antibody; ADCY4_HUMAN antibody; Adenylate cyclase 4 antibody; Adenylate cyclase type 4 antibody; Adenylate cyclase type IV antibody; Adenylyl cyclase 4 antibody; Adenylyl cyclase antibody; ATP pyrophosphate lyase 4 antibody; ATP pyrophosphate lyase antibody; ATP pyrophosphate-lyase 4 antibody
Raised in
Rabbit
Species Reactivity
Human
Immunogen
Recombinant Human Adenylate cyclase type 4 protein (808-1077AA)
Immunogen Species
Homo sapiens (Human)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form
Liquid
Tested Applications
ELISA, IHC
Recommended Dilution
Application Recommended Dilution
IHC 1:20-1:200
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.
Gene References into Functions
  1. AC4 and AC2, both isoforms stimulated by Gbetagamma, are expressed in bronchial nonlipid raft membrane fractions where they colocalize with and couple to prostanoid EP2 receptors. PMID: 21228062
  2. This paper reports the presence of adenylyl cyclases 2, 3, and 4 in mouse olfactory cilia. PMID: 11055432
  3. The HIV-1 regulatory protein Tat was shown to inhibit the activity of adenylyl cyclase in rat microglial cells. PMID: 11299302
Subcellular Location
Cell membrane; Multi-pass membrane protein. Cytoplasm.
Protein Families
Adenylyl cyclase class-4/guanylyl cyclase family
Tissue Specificity
Detected in the zona glomerulosa and the zona fasciculata in the adrenal gland (at protein level).
Database Links

HGNC: 235

OMIM: 600292

KEGG: hsa:196883

STRING: 9606.ENSP00000312126

UniGene: Hs.443428

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7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA
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