BDNF polyclonal antibody CSB-PA05775A0Rb was produced in the rabbit immunized by using the Recombinant Human Brain-derived neurotrophic factor protein (137-237AA) as the immunogen. The target protein BDNF, a member of the nerve growth factor family of proteins, is an important signaling molecule that activates signaling cascades downstream of NTRK2. During development, it promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Diseases associated with BDNF include Central Hypoventilation Syndrome, Congenital and Wilms Tumor, Aniridia, Genitourinary Anomalies, and Mental Retardation Syndrome.
This Rabbit anti-Homo sapiens (Human) BDNF Polyclonal antibody was tested in the ELISA, WB and IHC applications. The non-conjugated IgG got purified by protein G and reached up to 95% in purity. It reacts with the BDNF proteins of human or mouse-origin and may be used to detect the endogenous levels of BDNF protein.