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| Code | CSB-PA040301 |
| Size | US$167 |
| Uniprot No. | Q99731 |
| Protocols | Immunohistochemistry (IHC) Protocol ELISA Protocol |
| Immunogen | Synthesized peptide derived from the Internal region of Human MIP-3β. |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | IHC,ELISA;IHC:1/100-1/300.ELISA:1/40000 |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Isotype | IgG |
| Alias | CCL19; ELC; MIP3B; SCYA19; C-C motif chemokine 19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible |
| Immunogen Species | Homo sapiens (Human) |
| Target Names | CCL19 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Database Links |
HGNC: 10617 OMIM: 602227 KEGG: hsa:6363 STRING: 9606.ENSP00000308815 UniGene: Hs.50002 |
| Pathway |
Chemokine signaling pathway
NF-kappa B signaling pathway |
CCL19 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-RA859522A0HU | CCL19 Antibody | Human | ELISA, IHC |
CCL19 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA004782GA01HU | CCL19 Antibody | Human | ELISA,WB,IHC |
| CSB-PA859522ZA01HU | CCL19 Antibody | Homo sapiens | ELISA, WB (ensure identification of antigen) |
CCL19 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP859522HU CSB-BP859522HU CSB-MP859522HU |
Recombinant Human C-C motif chemokine 19(CCL19) | Yeast Baculovirus Mammalian cell |
| CSB-EP859522HU | Recombinant Human C-C motif chemokine 19(CCL19) | E.coli |
CCL19 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04670h | Human Macrophage Inflammatory Protein-3β,MIP-3β ELISA kit | serum, plasma, tissue homogenates | 9.75 pg/ml |
2-hydroxyisobutyryl-HIST1H2BC (K34) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
2-hydroxyisobutyryl-HIST1H3A (K23) Antibody
Applications: ELISA, WB, IF, ChIP
Species Reactivity: Human
