Your Good Partner in Biology Research
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Your Good Partner in Biology Research
| Code | CSB-PA040301 |
| Size | US$167 |
| Uniprot No. | Q99731 | ||||||
| Target Names | CCL19 | ||||||
| Alternative Names | CCL19; ELC; MIP3B; SCYA19; C-C motif chemokine 19; Beta-chemokine exodus-3; CK beta-11; Epstein-Barr virus-induced molecule 1 ligand chemokine; EBI1 ligand chemokine; ELC; Macrophage inflammatory protein 3 beta; MIP-3-beta; Small-inducible | ||||||
| Raised in | Rabbit | ||||||
| Species Reactivity | Human | ||||||
| Immunogen | Synthesized peptide derived from the Internal region of Human MIP-3β. | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated | ||||||
| Isotype | IgG | ||||||
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||||||
| Form | Liquid | ||||||
| Tested Applications | IHC, ELISA | ||||||
| Recommended Dilution |
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| Protocols | Immunohistochemistry (IHC) Protocol ELISA Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Database Links |
HGNC: 10617 OMIM: 602227 KEGG: hsa:6363 STRING: 9606.ENSP00000308815 UniGene: Hs.50002 |
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