Your Good Partner in Biology Research
Tel : 301-363-4651
Your Good Partner in Biology Research
| Code | CSB-PA004782GA01HU |
| Product Type | Purified Rabbit Anti human PolyClonal Antibody |
| Size | US$685 |
| Uniprot No. | Q99731 |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Immunogen | Human CCL19 |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA,WB,IHC |
| Storage Buffer | PBS with 0.02% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles. |
| Purification Method | Antigen Affinity Purified |
| Isotype | IgG |
| Alias | chemokine (C-C motif) ligand 19;CCL19;CKb11;ELC;MGC34433;MIP-3b;MIP3B;SCYA19 ; |
| Immunogen Species | Homo sapiens (Human) |
| Target Names | CCL19 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Target Details | This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The cytokine encoded by this gene may play a role in normal lymphocyte recirculation and homing. It also plays an important role in trafficking of T cells in thymus, and in T cell and B cell migration to secondary lymphoid organs. It specifically binds to chemokine receptor CCR7. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | May play a role not only in inflammatory and immunological responses but also in normal lymphocyte recirculation and homing. May play an important role in trafficking of T-cells in thymus, and T-cell and B-cell migration to secondary lymphoid organs. Binds to chemokine receptor CCR7. Recombinant CCL19 shows potent chemotactic activity for T-cells and B-cells but not for granulocytes and monocytes. Binds to atypical chemokine receptor ACKR4 and mediates the recruitment of beta-arrestin (ARRB1/2) to ACKR4. |
| Subcellular Location | Secreted |
| Protein Families | Intercrine beta (chemokine CC) family |
| Tissue Specificity | Expressed at high levels in the lymph nodes, thymus and appendix. Intermediate levels seen in colon and trachea, while low levels found in spleen, small intestine, lung, kidney and stomach. |
| Database Links |
HGNC: 10617 OMIM: 602227 KEGG: hsa:6363 STRING: 9606.ENSP00000308815 UniGene: Hs.50002 |
| Pathway |
Chemokine signaling pathway
NF-kappa B signaling pathway |
CCL19 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-RA859522A0HU | CCL19 Antibody | Human | ELISA, IHC |
CCL19 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA859522ZA01HU | CCL19 Antibody | Homo sapiens | ELISA, WB (ensure identification of antigen) |
| CSB-PA040301 | CCL19 Antibody | Human | IHC,ELISA |
CCL19 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP859522HU CSB-BP859522HU CSB-MP859522HU |
Recombinant Human C-C motif chemokine 19(CCL19) | Yeast Baculovirus Mammalian cell |
| CSB-EP859522HU | Recombinant Human C-C motif chemokine 19(CCL19) | E.coli |
CCL19 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E04670h | Human Macrophage Inflammatory Protein-3β,MIP-3β ELISA kit | serum, plasma, tissue homogenates | 9.75 pg/ml |
2-hydroxyisobutyryl-HIST1H3A (K4) Antibody
Applications: ELISA, WB, ICC, IF
Species Reactivity: Human
