CD70 Antibody

Datasheet
Code CSB-PA615999
Size US$299
Uniprot No. P32970
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA615999(CD70 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA615999(CD70 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: ×200)
Protocols ELISA Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Synthetic peptide of Human CD70
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA,IHC;ELISA:1:2000-1:5000,IHC:1:25-1:100
Relevance The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF27/CD27. It is a surface antigen on activated, but not on resting, T and B lymphocytes. It induces proliferation of costimulated T cells, enhances the generation of cytolytic T cells, and contributes to T cell activation. This cytokine is also reported to play a role in regulating B-cell activation, cytotoxic function of natural killer cells, and immunoglobulin sythesis.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias CD70 molecule
Immunogen Species Homo sapiens (Human)
Target Names CD70
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Cytokine that binds to CD27. Plays a role in T-cell activation. Induces the proliferation of costimulated T-cells and enhances the generation of cytolytic T-cells.
Subcellular Location Membrane, Single-pass type II membrane protein
Protein Families Tumor necrosis factor family
Database Links

HGNC: 11937

OMIM: 602840

KEGG: hsa:970

STRING: 9606.ENSP00000245903

UniGene: Hs.501497

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