Your Good Partner in Biology Research
Your Good Partner in Biology Research
| Code | CSB-PA273524 |
| Size | US$299 |
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| Have Questions? | Leave a Message or Start an on-line Chat |
| Uniprot No. | Q8WTT0 | ||||||
| Target Names | CLEC4C | ||||||
| Alternative Names | CLEC4C antibody; BDCA2 antibody; CLECSF11 antibody; CLECSF7 antibody; DLEC antibody; HECL antibody; UNQ9361/PRO34150C-type lectin domain family 4 member C antibody; Blood dendritic cell antigen 2 antibody; BDCA-2 antibody; C-type lectin superfamily member 7 antibody; Dendritic lectin antibody; CD antigen CD303 antibody | ||||||
| Raised in | Rabbit | ||||||
| Species Reactivity | Human | ||||||
| Immunogen | Synthetic peptide of Human CLEC4C | ||||||
| Immunogen Species | Homo sapiens (Human) | ||||||
| Conjugate | Non-conjugated | ||||||
| Isotype | IgG | ||||||
| Purification Method | Antigen affinity purification | ||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||
| Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol | ||||||
| Form | Liquid | ||||||
| Tested Applications | ELISA,IHC | ||||||
| Recommended Dilution |
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| Protocols | ELISA Protocol Immunohistochemistry (IHC) Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function (From Uniprot) |
Lectin-type cell surface receptor which may play a role in antigen capturing by dendritic cells. Specifically recognizes non-sialylated galactose-terminated biantennary glycans containing the trisaccharide epitope Gal(beta1-3/4)GlcNAc(beta1-2)Man. Binds to serum IgG. Efficiently targets ligand into antigen-processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and mobilizes intracellular calcium.
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| Gene References into Functions |
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| Subcellular Location | Cell membrane; Single-pass type II membrane protein. |
| Tissue Specificity | Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not with TNF-alpha. |
| Database Links |
HGNC: 13258 OMIM: 606677 KEGG: hsa:170482 STRING: 9606.ENSP00000353500 UniGene: Hs.351812 |
