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| Code | CSB-PA888016LC01HU |
| Size | US$299 |
| Uniprot No. | Q9HB29 |
| Immunogen | Recombinant Human Interleukin-1 receptor-like 2 protein (20-218AA) |
| Raised in | Rabbit |
| Species Reactivity | Human |
| Tested Applications | ELISA |
| Relevance | Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. |
| Form | Liquid |
| Conjugate | FITC |
| Storage Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method | >95%, Protein G purified |
| Isotype | IgG |
| Clonality | Polyclonal |
| Alias | Interleukin-1 receptor-like 2 (IL-36 receptor) (IL-36R) (Interleukin-1 receptor-related protein 2) (IL-1Rrp2) (IL1R-rp2), IL1RL2, IL1RRP2 |
| Immunogen Species | Human |
| Protocols | ELISA Protocol |
| Research Area | Immunology |
| Target Names | IL1RL2 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. |
| Subcellular Location | Membrane, Single-pass type I membrane protein |
| Protein Families | Interleukin-1 receptor family |
| Tissue Specificity | Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level. |
| Database Links |
HGNC: 5999 OMIM: 604512 KEGG: hsa:8808 STRING: 9606.ENSP00000264257 UniGene: Hs.659863 |
IL1RL2 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA888016LA01HU | IL1RL2 Antibody | Human | ELISA, IHC |
| CSB-PA888016LB01HU | IL1RL2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA888016LD01HU | IL1RL2 Antibody, Biotin conjugated | Human | ELISA |
IL1RL2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-AP004541HU | Recombinant Human Interleukin-1 receptor-like 2(IL1RL2),partial | Mammalian cell |
| CSB-YP888016HU CSB-EP888016HU CSB-BP888016HU CSB-MP888016HU |
Recombinant Human Interleukin-1 receptor-like 2(IL1RL2),partial | Yeast E.coli Baculovirus Mammalian cell |
IL1RL2 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL011627HU | Human Interleukin-1 receptor-like 2(IL1RL2) ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
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