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| Code | CSB-AP004541HU |
| Product Type | Interleukin |
| Size |
$117Purchase it in Cusabio online store (only available for customers from the US) |
| Uniprot No. | Q9HB29 |
| Image |
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| Storage Buffer | Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4 |
| Alias | Interleukin-1 receptor-like 2;IL1RL2;IL-36 receptor;IL-36R;IL-1Rrp2;IL1R-rp2; |
| Species | Homo sapiens (Human) |
| Biological_Activity | The ED50 as determined by its ability to bind Human IL-1F5 in functional ELISA is less than 50 ug/ml. |
| Purity | Greater than 95% as determined by SDS-PAGE. |
| Endotoxin | Less than 1.0 EU/μg as determined by LAL method. |
| Sequence | DGCKDIFMKNEILSASQPFAFNCTFPPITSGEVSVTWYKNSSKIPVSKIIQSRIHQDETWILFLPMEWGDSGVYQCVIKGRDSCHRIHVNLTVFEKHWCDTSIGGLPNLSDEYKQILHLGKDDSLTCHLHFPKSCVLGPIKWYKDCNEIKGERFTVLETRLLVSNVSAEDRGNYACQAILTHSGKQYEVLNGITVSITERAGYGGSVPKIIYPKNHSIEVQLGTTLIVDCNVTDTKDNTNLRCWRVNNTLVDDYYDESKRIREGVETHVSFREHNLYTVNITFLEVKMEDYGLPFMCHAGVSTAYIILQLPAPDFRAY |
| Research Area | Immunology |
| Source | Mammalian cell |
| Gene Names | IL1RL2 |
| Expression Region | 20-337aa |
| Tag Info | C-terminal FC-tagged |
| Mol. Weight | 63.1 kDa |
| Protein Description | Partial |
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| Function | Receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways (By similarity). The IL-36 signaling system is thought to be present in epithelial barriers and to take part in local inflammatory response; it is similar to the IL-1 system. Seems to be involved in skin inflammatory response by induction of the IL-23/IL-17/IL-22 pathway. |
| Subcellular Location | Membrane, Single-pass type I membrane protein |
| Protein Families | Interleukin-1 receptor family |
| Tissue Specificity | Expressed in synovial fibroblasts and articular chondrocytes. Expressed in keratinocytes and monocyte-derived dendritic cells. Expressed in monocytes and myeloid dendritic cells; at protein level. |
| Database Links |
HGNC: 5999 OMIM: 604512 KEGG: hsa:8808 STRING: 9606.ENSP00000264257 UniGene: Hs.659863 |
IL1RL2 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA888016LA01HU | IL1RL2 Antibody | Human | ELISA, IHC |
| CSB-PA888016LB01HU | IL1RL2 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA888016LC01HU | IL1RL2 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA888016LD01HU | IL1RL2 Antibody, Biotin conjugated | Human | ELISA |
IL1RL2 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP888016HU CSB-EP888016HU CSB-BP888016HU CSB-MP888016HU |
Recombinant Human Interleukin-1 receptor-like 2(IL1RL2),partial | Yeast E.coli Baculovirus Mammalian cell |
IL1RL2 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL011627HU | Human Interleukin-1 receptor-like 2(IL1RL2) ELISA kit | serum, plasma, tissue homogenates | 0.039 ng/mL |
Recombinant Human Zinc finger protein GLI2(GLI2),partial
Express system: Yeast
Species: Homo sapiens (Human)
Recombinant Mouse Muellerian-inhibiting factor(Amh) ,partial
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Mouse Nuclear receptor ROR-gamma(Rorc)
Express system: Yeast
Species: Mus musculus (Mouse)
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Recombinant Human Aquaporin-1(AQP1)
Express system: in vitro E.coli expression system
Species: Homo sapiens (Human)
Recombinant Human Ras-related protein Rab-10(RAB10),partial
Express system: E.coli
Species: Homo sapiens (Human)
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