ITGA2 Antibody

Datasheet
Code CSB-PA006197
Size US$167
Uniprot No. P17301
Image
  • Western Blot analysis of 3T3 cells using Integrin α2 Polyclonal Antibody
  • Western Blot analysis of NIH-3T3 cells using Integrin α2 Polyclonal Antibody
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from the C-terminal region of Human Integrin α2.
Raised in Rabbit
Species Reactivity Human,Mouse,Rat
Tested Applications WB,ELISA;WB:1/500-1/2000.ELISA:1/10000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias ITGA2; CD49B; Integrin alpha-2; CD49 antigen-like family member B; Collagen receptor; Platelet membrane glycoprotein Ia; GPIa; VLA-2 subunit alpha; CD49b
Immunogen Species Homo sapiens (Human)
Target Names ITGA2
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Integrin alpha-2/beta-1 is a receptor for laminin, collagen, collagen C-propeptides, fibronectin and E-cadherin. It recognizes the proline-hydroxylated sequence G-F-P-G-E-R in collagen. It is responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix.; FUNCTION
Subcellular Location Membrane, Single-pass type I membrane protein
Protein Families Integrin alpha chain family
Database Links

HGNC: 6137

OMIM: 192974

KEGG: hsa:3673

STRING: 9606.ENSP00000296585

UniGene: Hs.482077

Pathway PI3K-Akt signaling pathway
Focal adhesion
Regulation of actin cytoskeleton
Hematopoietic cell lineage

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