ITGA2

ITGA2, the integrin α2 subunit, alias CD49b, GPIa, HPA-5, VLA-2, is a 150 kDa membrane surface glycoprotein expressed in a variety of cell types such as platelets, intestinal epithelial cells, NK cells, epithelial cells and activated T cells.
The mechanism of action of ITGA2 is non-covalent binding to CD29 (integrin β1) to form a heterodimer, VLA-2, platelet glycoprotein Ia/IIa (CD49b/CD29), which mediates adhesion between mature megakaryocytes and platelets and collagen.ITGA2 plays an important role in extracellular matrix cell adhesion and is involved in cell adhesion, migration, proliferation and signaling processes, and is essential for maintaining the structural and functional integrity of tissues. Abnormal ITGA2 expression has been associated with a variety of diseases, including several arterial diseases, platelet disorders, and diabetes.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

ITGA2 Antibody (CSB-PA006197)

Validated Data

Western Blot analysis of 3T3 cells using Integrin α2 Polyclonal Antibody

Western Blot analysis of NIH-3T3 cells using Integrin α2 Polyclonal Antibody

Human Integrin alpha-2(ITGA2) ELISA kit (CSB-EL011864HU)

Validated Data

Code: CSB-EL011864HU

Size: 96T,5×96T,10×96T

Sensitivity: 0.058 ng/mL

Detection Range: 0.235 ng/mL-15 ng/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following ITGA2 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

ITGA2 Antibodies

ITGA2 Proteins

ITGA2 ELISA Kits

ITGA2 Antibodies

ITGA2 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA006197	ITGA2 Antibody	Human,Mouse,Rat	WB, ELISA
CSB-PA938467	ITGA2 Antibody	Human	ELISA,WB,IHC
CSB-PA079340	ITGA2 Antibody	Human	ELISA,WB,IHC
CSB-PA011864LA01HU	ITGA2 Antibody	Human	ELISA, IHC, IF
CSB-PA011864LD01HU	ITGA2 Antibody, Biotin conjugated	Human	ELISA

ITGA2 Proteins

ITGA2 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP011864HU	Recombinant Human Integrin alpha-2 (ITGA2), partial	Yeast
CSB-EP011864HU	Recombinant Human Integrin alpha-2 (ITGA2), partial	E.coli
CSB-BP011864HU CSB-MP011864HU CSB-EP011864HU-B	Recombinant Human Integrin alpha-2 (ITGA2), partial	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP011864HUb0	Recombinant Human Integrin alpha-2 (ITGA2), partial	E.coli

ITGA2 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-YP011864BO CSB-EP011864BO CSB-BP011864BO CSB-MP011864BO CSB-EP011864BO-B	Recombinant Bovine Integrin alpha-2 (ITGA2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ITGA2 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP714022MO CSB-EP714022MO CSB-BP714022MO CSB-MP714022MO CSB-EP714022MO-B	Recombinant Mouse Integrin alpha-2 (Itga2), partial	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

ITGA2 ELISA Kit

ITGA2 ELISA Kit for Homo sapiens (Human)

Code	Product Name	Sample Types	Sensitivity
CSB-EL011864HU	Human Integrin alpha-2(ITGA2) ELISA kit	serum, plasma, tissue homogenates	0.058 ng/mL

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ITGA2

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