MOV10 Antibody

Datasheet
Code CSB-PA862068LA01HU
See More Details
Size US$299Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. Q9HCE1
Image
  • Western blot
    All lanes: MOV10 antibody at 0.4µg/ml
    Lane 1: HepG2 whole cell lysate
    Lane 2: 293T whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 114, 102, 7 kDa
    Observed band size: 114 kDa

  • Immunohistochemistry of paraffin-embedded human testis tissue using CSB-PA862068LA01HU at dilution of 1:100

Immunogen Recombinant Human Putative helicase MOV-10 protein (601-900AA)
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA, WB, IHC; Recommended dilution: WB:1:1000-1:5000, IHC:1:20-1:200
Relevance Probable RNA helicase. Required for RNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. Also required for RNA-directed transcription and replication of the human hepatitis delta virus (HDV). Interacts with small capped HDV RNAs derived from genomic hairpin structures that mark the initiation sites of RNA-dependent HDV RNA transcription.
Form Liquid
Conjugate Non-conjugated
Storage Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method Antigen Affinity Purified
Isotype IgG
Clonality Polyclonal
Alias Putative helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein), MOV10, KIAA1631
Immunogen Species Human
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Research Area Epigenetics and Nuclear Signaling
Target Names MOV10
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
References
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Function Probable RNA helicase. Required for miRNA-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC.
Subcellular Location Cytoplasm, P-body
Protein Families DNA2/NAM7 helicase family, SDE3 subfamily
Database Links

HGNC: 7200

OMIM: 610742

KEGG: hsa:4343

STRING: 9606.ENSP00000350028

UniGene: Hs.514941

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