MOV10 is a protein in humans that is encoded by MOV10 gene. 5' to 3' RNA helicase contributing to UPF1 mRNA target degradation by translocation along 3' UTRs (PubMed. Required for microRNA (miRNA)-mediated gene silencing by the RNA-induced silencing complex (RISC). Required for both miRNA-mediated translational repression and miRNA-mediated cleavage of complementary mRNAs by RISC. In cooperation with FMR1, regulates miRNA-mediated translational repression by AGO2. Restricts retrotransposition of long interspersed element-1 (LINE-1) in cooperation with TUT4 and TUT7 counteracting the RNA chaperonne activity of L1RE1. Facilitates LINE-1 uridylation by TUT4 and TUT7. Required for embryonic viability and for normal central nervous system development and function. Plays two critical roles in early brain development suppresses retroelements in the nucleus by directly inhibiting cDNA synthesis, while regulates cytoskeletal mRNAs to influence neurite outgrowth in the cytosol (By similarity). May function as a messenger ribonucleoprotein (mRNP) clearance factor. Exhibits antiviral activity against dengue virus (DENV).
The following MOV10 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.
MOV10 Antibodies for Homo sapiens (Human)
Code | Product Name | Species Reactivity | Application |
---|---|---|---|
CSB-PA014739GA01HU | MOV10 Antibody |
Human,Mouse,Rat | ELISA,WB,IHC |
CSB-PA862068LA01HU | MOV10 Antibody |
Human | ELISA, WB, IHC |
CSB-PA862068LB01HU | MOV10 Antibody, HRP conjugated |
Human | ELISA |
CSB-PA862068LC01HU | MOV10 Antibody, FITC conjugated |
Human | |
CSB-PA862068LD01HU | MOV10 Antibody, Biotin conjugated |
Human | ELISA |
MOV10 Proteins for Mus musculus (Mouse)
Code | Product Name | Source |
---|---|---|
CSB-YP014739MO CSB-EP014739MO CSB-BP014739MO CSB-MP014739MO CSB-EP014739MO-B |
Recombinant Mouse Putative helicase MOV-10 (Mov10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MOV10 Proteins for Bos taurus (Bovine)
Code | Product Name | Source |
---|---|---|
CSB-YP607138BO CSB-EP607138BO CSB-BP607138BO CSB-MP607138BO CSB-EP607138BO-B |
Recombinant Bovine Putative helicase MOV-10 (MOV10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MOV10 Proteins for Gallus gallus (Chicken)
Code | Product Name | Source |
---|---|---|
CSB-YP713739CH CSB-EP713739CH CSB-BP713739CH CSB-MP713739CH CSB-EP713739CH-B |
Recombinant Chicken Putative helicase MOV-10 (MOV10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
MOV10 Proteins for Homo sapiens (Human)
Code | Product Name | Source |
---|---|---|
CSB-YP862068HU CSB-EP862068HU CSB-BP862068HU CSB-MP862068HU CSB-EP862068HU-B |
Recombinant Human Putative helicase MOV-10 (MOV10), partial |
Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |