Ms4a1 Antibody

Code CSB-PA015007LA01MO
Size US$166
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  • Western blot
    All lanes: Ms4a1 antibody at 4µg/ml
    Lane 1: Hela whole cell lysate
    Lane 2: Jurkat whole cell lysate
    Lane 3: 293T whole cell lysate
    Lane 4: HL60 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 32 kDa
    Observed band size: 32 kDa
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Product Details

Full Product Name
Rabbit anti-Mus musculus (Mouse) Ms4a1 Polyclonal antibody
Uniprot No.
Target Names
Ms4a1
Alternative Names
Ms4a1 antibody; Cd20 antibody; Ly-44 antibody; Ms4a2 antibody; B-lymphocyte antigen CD20 antibody; B-cell differentiation antigen Ly-44 antibody; Lymphocyte antigen 44 antibody; Membrane-spanning 4-domains subfamily A member 1 antibody; CD antigen CD20 antibody
Raised in
Rabbit
Species Reactivity
Mouse, Human
Immunogen
Recombinant Mouse B-lymphocyte antigen CD20 protein (111-291AA)
Immunogen Species
Mus musculus (Mouse)
Conjugate
Non-conjugated

The Ms4a1 Antibody (Product code: CSB-PA015007LA01MO) is Non-conjugated. For Ms4a1 Antibody with conjugates, please check the following table.

Available Conjugates
Conjugate Product Code Product Name Application
HRP CSB-PA015007LB01MO Ms4a1 Antibody, HRP conjugated ELISA
FITC CSB-PA015007LC01MO Ms4a1 Antibody, FITC conjugated
Biotin CSB-PA015007LD01MO Ms4a1 Antibody, Biotin conjugated ELISA
Clonality
Polyclonal
Isotype
IgG
Purification Method
>95%, Protein G purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Form
Liquid
Tested Applications
ELISA, WB
Recommended Dilution
Application Recommended Dilution
WB 1:1000-1:5000
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function
B-lymphocyte-specific membrane protein that plays a role in the regulation of cellular calcium influx necessary for the development, differentiation, and activation of B-lymphocytes. Functions as a store-operated calcium (SOC) channel component promoting calcium influx after activation by the B-cell receptor/BCR.
Gene References into Functions
  1. Our findings indicate that anti-CD20-IFNalpha eradicates B-cell lymphoma by employing tumor cells as antigen-presenting cells to reactivate tumor-infiltrating CD8(+) T cells and synergizing with anti-PD-L1 treatment PMID: 28533311
  2. Galectin-1 has a role in driving lymphoma CD20 immunotherapy resistance in a mouse model PMID: 26888257
  3. Results indicate that an antigen-specific B cell response towards intracellular pathogens can be generated during anti-CD20 depletion therapy. PMID: 26261496
  4. this study demonstrates a role for CD20 in B cell activation and T-dependent humoral immunity. PMID: 23966626
  5. CD20 is required for store-operated calcium entry in C2C12 myoblasts. PMID: 22982241
  6. immunization of mice with the CD20 extracellular domain-6 using Freund's or QS-21 adjuvants was shown to exert significant biological effects in vivo with the pronounced depletion of splenic B cells. PMID: 20189250
  7. type I CD20 antibody cytotoxicity critically depends on Fc receptor ITAM signaling PMID: 20354182
  8. CD20 deficiency in humans results in impaired T cell-independent antibody responses. PMID: 20038800
  9. review of structure, function, tissue and cell distribution PMID: 12144126
  10. Anti-CD20 antibodies rapidly depleted the vast majority of circulating and tissue B cells in an isotype-restricted manner dependent on effector cell Fc receptor expression. PMID: 15210744
  11. expression in bacterial cells; isolation and biophysical and structural studies PMID: 16285718
  12. In mice treated with anti-CD20 mAb, development of arthritis was significantly reduced in comparison to control mAb-treated mice PMID: 18354225
  13. involvement of CD20 in calcium influx PMID: 18474602

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Subcellular Location
Cell membrane; Multi-pass membrane protein. Cell membrane; Lipid-anchor.
Protein Families
MS4A family
Database Links
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