NGF Antibody

Datasheet

Code	CSB-PA643662LA01PI
Size	US$166
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Product Details

Full Product Name

Rabbit anti-Sus scrofa (Pig) NGF Polyclonal antibody

Uniprot No.

Q29074

Target Names

NGF

Alternative Names

NGF antibody; NGFB antibody; Beta-nerve growth factor antibody; Beta-NGF antibody; Fragment antibody

Raised in

Rabbit

Species Reactivity

Pig

Immunogen

Recombinant Pig Beta-nerve growth factor protein (110-229AA)

Immunogen Species

Sus scrofa (Pig)

Conjugate

Non-conjugated

The NGF Antibody (Product code: CSB-PA643662LA01PI) is Non-conjugated. For NGF Antibody with conjugates, please check the following table.

Conjugate	Product Code	Product Name	Application
HRP	CSB-PA643662LB01PI	NGF Antibody, HRP conjugated	ELISA
FITC	CSB-PA643662LC01PI	NGF Antibody, FITC conjugated
Biotin	CSB-PA643662LD01PI	NGF Antibody, Biotin conjugated	ELISA

Clonality

Polyclonal

Isotype

IgG

Purification Method

>95%, Protein G purified

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form

Liquid

Tested Applications

ELISA

Protocols

ELISA Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function

Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival. The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI. Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form.

Subcellular Location

Secreted. Endosome lumen.

Protein Families

NGF-beta family

Database Links

STRING: 9823.ENSSSCP00000007197

UniGene: Ssc.19976

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Related pathways

MAPK signaling pathway PI3K-Akt signaling pathway Apoptosis Ras signaling pathway Rap1 signaling pathway Inflammatory Pain Inhibitors of axonal regeneration

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

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Address

7505 Fannin St., Ste 610, Room 322 (CUBIO Innovation Center), Houston, TX 77054, USA

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NGF Antibody

Product Details

Related Products

Customer Reviews and Q&A

Target Background