Your Good Partner in Biology Research
Your Good Partner in Biology Research
| Code | CSB-PA643662LC01PI |
| Size | US$299 |
| Have Questions? | Leave a Message or Start an on-line Chat |
| Full Product Name | Rabbit anti-Sus scrofa (Pig) NGF Polyclonal antibody |
| Uniprot No. | Q29074 |
| Target Names | NGF |
| Alternative Names | NGF antibody; NGFB antibody; Beta-nerve growth factor antibody; Beta-NGF antibody; Fragment antibody |
| Raised in | Rabbit |
| Species Reactivity | Pig |
| Immunogen | Recombinant Pig Beta-nerve growth factor protein (110-229AA) |
| Immunogen Species | Sus scrofa (Pig) |
| Conjugate | FITC |
| Clonality | Polyclonal |
| Isotype | IgG |
| Purification Method | >95%, Protein G purified |
| Concentration | It differs from different batches. Please contact us to confirm it. |
| Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Form | Liquid |
| Troubleshooting and FAQs | Antibody FAQs |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. |
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| Function (From Uniprot) |
Nerve growth factor is important for the development and maintenance of the sympathetic and sensory nervous systems. Extracellular ligand for the NTRK1 and NGFR receptors, activates cellular signaling cascades to regulate neuronal proliferation, differentiation and survival. The immature NGF precursor (proNGF) functions as ligand for the heterodimeric receptor formed by SORCS2 and NGFR, and activates cellular signaling cascades that lead to inactivation of RAC1 and/or RAC2, reorganization of the actin cytoskeleton and neuronal growth cone collapse. In contrast to mature NGF, the precursor form (proNGF) promotes neuronal apoptosis (in vitro). Inhibits metalloproteinase-dependent proteolysis of platelet glycoprotein VI. Binds lysophosphatidylinositol and lysophosphatidylserine between the two chains of the homodimer. The lipid-bound form promotes histamine relase from mast cells, contrary to the lipid-free form.
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| Subcellular Location | Secreted. Endosome lumen. |
| Protein Families | NGF-beta family |
| Database Links |
STRING: 9823.ENSSSCP00000007197 UniGene: Ssc.19976 |
