Your Good Partner in Biology Research
Tel : 301-363-4651
Your Good Partner in Biology Research
| Code | CSB-PA020236 |
| Size | US$167 |
| Uniprot No. | O60260 | ||||||||||
| Target Names | PRKN | ||||||||||
| Alternative Names | PARK2; PRKN; E3 ubiquitin-protein ligase parkin; Parkinson juvenile disease protein 2; Parkinson disease protein 2 | ||||||||||
| Raised in | Rabbit | ||||||||||
| Species Reactivity | Human,Mouse,Rat | ||||||||||
| Immunogen | Synthesized peptide derived from the N-terminal region of Human PARK2. | ||||||||||
| Immunogen Species | Homo sapiens (Human) | ||||||||||
| Conjugate | Non-conjugated | ||||||||||
| Isotype | IgG | ||||||||||
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | ||||||||||
| Concentration | It differs from different batches. Please contact us to confirm it. | ||||||||||
| Buffer | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. | ||||||||||
| Form | Liquid | ||||||||||
| Tested Applications | WB, IHC, IF, ELISA | ||||||||||
| Recommended Dilution |
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| Protocols | Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol ELISA Protocol |
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| Troubleshooting and FAQs | Antibody FAQs | ||||||||||
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||||||
| Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||||||
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIMP2 |
| Involvement in disease | Parkinson disease (PARK); Parkinson disease 2 (PARK2) |
| Subcellular Location | Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion |
| Protein Families | RBR family, Parkin subfamily |
| Tissue Specificity | Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons fro |
| Database Links |
HGNC: 8607 OMIM: 168600 KEGG: hsa:5071 STRING: 9606.ENSP00000355865 UniGene: Hs.132954 |
2-hydroxyisobutyryl-HIST1H1C (K158) Antibody
Applications: ELISA, WB, ICC, ChIP
Species Reactivity: Human
Tel: 301-363-4651
Email: support@cusabio.com
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