Code | CSB-PA017451LA01HU |
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US$299Purchase it in Cusabio online store (only available for customers from the US) |
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Full Product Name | Rabbit anti-Human PRKN Polyclonal antibody | ||||||||
Uniprot No. | O60260 | ||||||||
Target Names | PRKN | ||||||||
Alternative Names | E3 ubiquitin-protein ligase parkin (Parkin) (EC 2.3.2.27) (Parkin RBR E3 ubiquitin-protein ligase) (Parkinson juvenile disease protein 2) (Parkinson disease protein 2), PRKN, PARK2 | ||||||||
Raised in | Rabbit | ||||||||
Species Reactivity | Human | ||||||||
Immunogen | Recombinant Human E3 ubiquitin-protein ligase parkin protein (1-465AA) | ||||||||
Immunogen Species | Human | ||||||||
Conjugate | Non-conjugated | ||||||||
Clonality | Polyclonal | ||||||||
Isotype | IgG | ||||||||
Purification Method | >95%, Protein G purified | ||||||||
Concentration | It differs from different batches. Please contact us to confirm it. | ||||||||
Buffer | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
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Form | Liquid | ||||||||
Tested Applications | ELISA, WB, IHC, IF | ||||||||
Recommended Dilution |
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Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol Immunofluorescence (IF) Protocol |
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Troubleshooting and FAQs | Antibody FAQs | ||||||||
Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. | ||||||||
Lead Time | Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time. | ||||||||
Still Have Questions? | Leave a Message or Start an on-line Chat |
Function | Functions within a multiprotein E3 ubiquitin ligase complex, catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins, such as BCL2, SYT11, CCNE1, GPR37, RHOT1/MIRO1, MFN1, MFN2, STUB1, SNCAIP, SEPT5, TOMM20, USP30, ZNF746 and AIMP2 |
Involvement in disease | Parkinson disease (PARK); Parkinson disease 2 (PARK2) |
Subcellular Location | Cytoplasm, cytosol, Nucleus, Endoplasmic reticulum, Mitochondrion |
Protein Families | RBR family, Parkin subfamily |
Tissue Specificity | Highly expressed in the brain including the substantia nigra. Expressed in heart, testis and skeletal muscle. Expression is down-regulated or absent in tumor biopsies, and absent in the brain of PARK2 patients. Overexpression protects dopamine neurons fro |
Database Links |
HGNC: 8607 OMIM: 168600 KEGG: hsa:5071 STRING: 9606.ENSP00000355865 UniGene: Hs.132954 |
2-hydroxyisobutyryl-HIST1H3A (K23) Antibody
Applications: ELISA, WB, IF, ChIP
Species Reactivity: Human
Tel: 301-363-4651
Email: support@cusabio.com
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