PPP1R15A Antibody

Datasheet
Code CSB-PA787946
Size US$167
Image
  • Western blot analysis of MOUSE-BRAIN lysate, antibody was diluted at 1000. Secondary antibody was diluted at 1:20000

Product Details

Uniprot No. O75807
Target Names PPP1R15A
Alternative Names Protein phosphatase 1 regulatory subunit 15A (Growth arrest and DNA damage-inducible protein GADD34) (Myeloid differentiation primary response protein MyD116 homolog)
Raised in Rabbit
Species Reactivity Human
Immunogen Synthetic peptide from Human protein at AA range: 430-490
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Purification Method The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS, pH 7.4, containing 0.02% sodium azide as Preservative and 50% Glycerol.
Form Liquid
Tested Applications WB,ELISA
Recommended Dilution
Application Recommended Dilution
WB 1:500-2000
ELISA 1:10000-20000
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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Target Data

Function Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on 'Ser-15'.
Subcellular Location Endoplasmic reticulum membrane, Peripheral membrane protein, Cytoplasmic side, Mitochondrion outer membrane, Peripheral membrane protein, Cytoplasmic side
Protein Families PPP1R15 family
Database Links

HGNC: 14375

OMIM: 611048

KEGG: hsa:23645

STRING: 9606.ENSP00000200453

UniGene: Hs.631593

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