PPP2CB Antibody

Code CSB-PA018560GA01HU
Size $600
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Product Details

Uniprot No.
Target Names
PPP2CB
Alternative Names
PP2A beta antibody; PP2A-beta antibody; PP2AB_HUMAN antibody; PP2Abeta antibody; PP2CB antibody; Ppp2cb antibody; Protein phosphatase 2 (formerly 2A); catalytic subunit; beta isoform antibody; Protein phosphatase 2 catalytic subunit beta isozyme antibody; Protein phosphatase 2; catalytic subunit; beta isoform antibody; Protein phosphatase 2A catalytic subunit beta isoform antibody; Protein phosphatase type 2A catalytic subunit antibody; Serine/threonine protein phosphatase 2A catalytic subunit beta antibody; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody
Raised in
Rabbit
Species Reactivity
Human,Mouse,Rat
Immunogen
Human PPP2CB
Immunogen Species
Homo sapiens (Human)
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Tested Applications
ELISA,WB
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time
Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Background

Function
PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.
Gene References into Functions
  1. The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability PMID: 21317290
  2. Claspin may be one of the phosphoproteins through which PP2A(Aalpha/Cbeta) affects Chk1 phosphorylation when ATR is activated by human immunodeficiency virus-1 Vpr. PMID: 17210576
  3. These data strongly support a recent proposal that a segment at 8p21.3 contains crucial prostate cancer tumor suppressors. PMID: 18460741
Subcellular Location
Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.
Protein Families
PPP phosphatase family, PP-1 subfamily
Database Links

HGNC: 9300

OMIM: 176916

KEGG: hsa:5516

STRING: 9606.ENSP00000221138

UniGene: Hs.491440

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301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)
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Address
7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA
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