PPP2CB Antibody

Datasheet

Code	CSB-PA920060
Size	US$166
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Image	The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using CSB-PA920060(PPP2CB Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200) Gel: 12%SDS-PAGE, Lysate: 40 μg, Lane: Jurkat cells, Primary antibody: CSB-PA920060(PPP2CB Antibody) at dilution 1/1200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
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Product Details
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Target Background

Product Details

Uniprot No.

P62714

Target Names

PPP2CB

Alternative Names

PP2A beta antibody; PP2A-beta antibody; PP2AB_HUMAN antibody; PP2Abeta antibody; PP2CB antibody; Ppp2cb antibody; Protein phosphatase 2 (formerly 2A); catalytic subunit; beta isoform antibody; Protein phosphatase 2 catalytic subunit beta isozyme antibody; Protein phosphatase 2; catalytic subunit; beta isoform antibody; Protein phosphatase 2A catalytic subunit beta isoform antibody; Protein phosphatase type 2A catalytic subunit antibody; Serine/threonine protein phosphatase 2A catalytic subunit beta antibody; Serine/threonine-protein phosphatase 2A catalytic subunit beta isoform antibody

Raised in

Rabbit

Species Reactivity

Human,Mouse,Rat

Immunogen

Synthetic peptide of Human PPP2CB

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,WB,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:10000
WB	1:1000-1:5000
IHC	1:50-1:200

Protocols

ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

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Target Background

Function

PP2A can modulate the activity of phosphorylase B kinase casein kinase 2, mitogen-stimulated S6 kinase, and MAP-2 kinase.

Gene References into Functions

The GAS41-PP2Cbeta complex dephosphorylates p53 at serine 366 and regulates its stability PMID: 21317290
Claspin may be one of the phosphoproteins through which PP2A(Aalpha/Cbeta) affects Chk1 phosphorylation when ATR is activated by human immunodeficiency virus-1 Vpr. PMID: 17210576
These data strongly support a recent proposal that a segment at 8p21.3 contains crucial prostate cancer tumor suppressors. PMID: 18460741

Subcellular Location

Cytoplasm. Nucleus. Chromosome, centromere. Cytoplasm, cytoskeleton, spindle pole. Note=In prometaphase cells, but not in anaphase cells, localizes at centromeres. During mitosis, also found at spindle poles.

Protein Families

PPP phosphatase family, PP-1 subfamily

Database Links

HGNC: 9300

OMIM: 176916

KEGG: hsa:5516

STRING: 9606.ENSP00000221138

UniGene: Hs.491440

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Service

Phage Display Service

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Protein Service

Gene Synthesis Service

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Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Hippo signaling pathway PI3K-Akt signaling pathway TGF-beta signaling pathway Autophagy AMPK signaling Sphingolipid signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

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