PPP3CC Antibody

Code CSB-PA018574ESR2HU
Size US$167Purchase it in Cusabio online store
(only available for customers from the US)
Image
  • Western blot
    All lanes: Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform antibody at 8μg/ml
    Lane 1: Rat brain tissue
    Lane 2: MCF-7 whole cell lysate
    Secondary
    Goat polyclonal to rabbit IgG at 1/10000 dilution
    Predicted band size: 59, 58, 60 kDa
    Observed band size: 59 kDa

  • Immunohistochemistry of paraffin-embedded human prostate tissue using CSB-PA018574ESR2HU at dilution of 1:100

  • Immunohistochemistry of paraffin-embedded human placenta tissue using CSB-PA018574ESR2HU at dilution of 1:100

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Product Details

Full Product Name Rabbit anti-Homo sapiens (Human) PPP3CC Polyclonal antibody
Uniprot No. P48454
Target Names PPP3CC
Alternative Names calcineurin A gamma antibody; CALCINEURIN A3 antibody; Calcineurin antibody; Calcineurin testis specific catalytic subunit antibody; Calmodulin dependent calcineurin A subunit gamma isoform antibody; Calmodulin-dependent calcineurin A subunit gamma isoform antibody; CALNA3 antibody; CAM PRP catalytic subunit antibody; CAM-PRP catalytic subunit antibody; CNA3 antibody; pp2b gamma Antibody antibody; PP2BC_HUMAN antibody; PP2Bgamma Antibody antibody; PPP3CC antibody; protein phosphatase 3 (formerly 2B) catalytic subunit gamma isoform (calcineurin A gamma) antibody; protein phosphatase 3 (formerly 2B) catalytic subunit gamma isoform antibody; Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform antibody; testis-specific catalytic subunit antibody
Raised in Rabbit
Species Reactivity Human, Rat
Immunogen Recombinant Human Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform protein (373-512AA)
Immunogen Species Homo sapiens (Human)
Conjugate Non-conjugated
Clonality Polyclonal
Isotype IgG
Purification Method Antigen Affinity Purified
Concentration It differs from different batches. Please contact us to confirm it.
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Form Liquid
Tested Applications ELISA, WB, IHC
Recommended Dilution
Application Recommended Dilution
WB 1:200-1:1000
IHC 1:20-1:200
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Lead Time Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

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Target Data

Function Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.
Gene References into Functions
  1. PPP3CC rs7431 may alter miRNA binding ability of miR-212 and miR-132, and thus decrease bladder cancer risk. PMID: 29275364
  2. These findings indicated that the down-regulation of PPP3CC by ZEB1 resulted in activation of NF-kappaB is a critical oncogenic event in gliomas. PMID: 29294030
  3. The rs2443504 AA genotype was associated with the Glasgow coma score at 3, 6, and 12 months following severe brain injury. PMID: 27225880
  4. Knockdown of CNAgamma leads to a disruption of synaptic vesicle cycling in hippocampal neurons. PMID: 26627835
  5. The PPP3CC involved in the regulation of immune system and synaptic plasticity, seems promising for further investigation. PMID: 24709691
  6. protein level of PPP3CC negatively correlates with the cellular level of IP3, suggesting a regulatory role of PPP3CC in the IP3-Ca2+ signaling pathway PMID: 23747857
  7. study suggests that NMDA receptor-mediated signalling genes, DAO, PPP3CC, DTNBP1 might be involved in schizophrenia pathogenic mechanisms related to gender PMID: 23497497
  8. This study demoistrated that PPP3CC are not genetic risk factors for schizophrenia in japanese. PMID: 20537399
  9. results identify PPP3CC, located at 8p21.3, as a potential schizophrenia susceptibility gene and support the proposal that alterations in calcineurin signaling contribute to schizophrenia pathogenesis PMID: 12851458
  10. Decreased hippocampal expression of the susceptibility gene PPP3CC in schizophrenia. PMID: 15820226
  11. PPP3CC may not play a major role in Japanese schizophrenia PMID: 15843870
  12. The results suggest that PPP3CC gene may be a true susceptibility gene for schizophrenia. PMID: 17339875
  13. The Polymorphism, Single Nucleotide of ppp3cc is assosciated with schizophrenia. PMID: 17895921
  14. No significant differences in calcineurin A gamma expression was observed between patients with schizophrenia and normal controls PMID: 18343007
  15. Data suggest that PPP3CC does not elevate the risk of methamphetamine-use disorder in the Japanese population. PMID: 18991849

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Protein Families PPP phosphatase family, PP-2B subfamily
Tissue Specificity Testis.
Database Links

HGNC: 9316

OMIM: 114107

KEGG: hsa:5533

STRING: 9606.ENSP00000240139

UniGene: Hs.731683

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