PRKACG Antibody

Datasheet

Code	CSB-PA942370
Size	US$166
	Order now
Image	The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA942370(PRKACG Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200) The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA942370(PRKACG Antibody) at dilution 1/25, on the right is treated with fusion protein. (Original magnification: ×200)
Have Questions?	Leave a Message or Start an on-line Chat

Product Details
Related Products
Customer Reviews and Q&A
Target Background

Product Details

Uniprot No.

P22612

Target Names

PRKACG

Alternative Names

cAMP-dependent protein kinase catalytic subunit gamma antibody; KAPCG_HUMAN antibody; KAPG antibody; PKA C gamma antibody; PKA C-gamma antibody; PKACg antibody; PRKACG antibody; Protein kinase cAMP dependent catalytic gamma antibody; Serine (threonine) protein kinase antibody

Raised in

Rabbit

Species Reactivity

Human

Immunogen

Fusion protein of Human PRKACG

Immunogen Species

Homo sapiens (Human)

Conjugate

Non-conjugated

Isotype

IgG

Purification Method

Antigen affinity purification

Concentration

It differs from different batches. Please contact us to confirm it.

Buffer

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form

Liquid

Tested Applications

ELISA,IHC

Recommended Dilution

Application	Recommended Dilution
ELISA	1:2000-1:5000
IHC	1:25-1:100

Protocols

ELISA Protocol
Immunohistochemistry (IHC) Protocol

Troubleshooting and FAQs

Antibody FAQs

Storage

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Lead Time

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.

Customer Reviews and Q&A

■ Customer Reviews

There are currently no reviews for this product.

Submit a Review here

Target Background

Function

Phosphorylates a large number of substrates in the cytoplasm and the nucleus.

Gene References into Functions

The missense p.74Ile>Met PRKACG mutation is associated with a marked defect in proplatelet formation and a low level in filamin A in megakaryocytes. PMID: 25061177
PKA-mediated phosphorylation of GPIbbeta at Ser(166) negatively regulates VWF binding to GPIb-IX and is one of the mechanisms by which PKA mediates platelet inhibition PMID: 12361948
Results suggest that Cgamma and Calpha differ in structure and function in vitro, supporting the hypothesis that functionally different C-subunit isozymes could affect cAMP signal transduction downstream of protein kinase A activation. PMID: 15039079

Involvement in disease

Bleeding disorder, platelet-type 19 (BDPLT19)

Protein Families

Protein kinase superfamily, AGC Ser/Thr protein kinase family, cAMP subfamily

Tissue Specificity

Testis specific. But important tissues such as brain and ovary have not been analyzed for the content of transcript.

Database Links

HGNC: 9382

OMIM: 176893

KEGG: hsa:5568

STRING: 9606.ENSP00000366488

UniGene: Hs.158029

Promotions

Transmembrane Protein Questionnaire with Gifts

Email: [email protected]
Distributors Worldwide

Service

Phage Display Service

Antibody Service

Protein Service

Gene Synthesis Service

Oligo Synthesis Service

Antibody FAQs What Is an Antibody? How to Choose an Antibody for Scientific Research? The difference between primary antibody and secondary antibod The Meaning of Irregular Antibody Screening Tag Antibodies, Your Good Partner in Protein Research How to Choose the Loading Control Antibodies?

Related pathways

Calcium signaling pathway cAMP signaling pathway Chemokine signaling pathway Estrogen signaling pathway Hedgehog signaling pathway MAPK signaling pathway Melanogenesis Wnt signaling pathway Gap junction Vascular smooth muscle contraction Autophagy Ras signaling pathway Th17 cell differentiation Apelin signaling pathway Glucagon signaling pathway Insulin signaling pathway Glutamatergic synapse G protein coupled receptor signaling pathway

Call us

301-363-4651 (Available 9 a.m. to 5 p.m. CST from Monday to Friday)

[email protected]

Address

7505 Fannin St., Ste 610, Room 7 (CUBIO Innovation Center), Houston, TX 77054, USA

Join us with

Subscribe newsletter

Leave a message

Message

Product >> Product Name：
Product >> Code：
Name： *
Email： *
Company/Organization：
Phone：
Since emails may get flagged by spam filters occasionally, we recommend leaving your phone number as a precaution. Your information is safe with us.
Question/Comment： *
Your Region： *
I'd like to receive email newsletters from Cusabio

Yes

No
How do you know CUSABIO?

Email

Distributor

Search engine

Advertisement

Others
CAPTCHA verification：

Place an order now

I. Product details

Product name *

Code *

Size *

Quantity *

Message

II. Contact details

Name *

Email address *

Company/Organization

Phone

III. Ship To

Address *

City *

State/Province *

Zip/Post code *

Country *

Attn Name *

Phone# *

IV. Bill To Same as Shipping Address