TP73 Antibody

Datasheet
Code CSB-PA003696
Size US$167
Uniprot No. O15350
Image
  • Western Blot analysis of 293T cells using p73 Polyclonal Antibody
  • Western Blot analysis of NIH-3T3 cells using p73 Polyclonal Antibody
  • Western Blot analysis of A549 using p73 Polyclonal Antibody.
Protocols Western Blotting(WB) Protocol
ELISA Protocol
Immunogen Synthesized peptide derived from Human p73 around the non-phosphorylation site of Y99.
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications WB,ELISA;WB:1/500-1/2000.ELISA:1/20000
Form Liquid
Conjugate Non-conjugated
Storage Buffer Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Isotype IgG
Alias TP73; P73; Tumor protein p73; p53-like transcription factor; p53-related protein
Immunogen Species Homo sapiens (Human)
Target Names TP73
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
Subcellular Location Nucleus, Cytoplasm
Protein Families P53 family
Tissue Specificity Expressed in striatal neurons of patients with Huntington disease (at protein level). Brain, kidney, placenta, colon, heart, liver, spleen, skeletal muscle, prostate, thymus and pancreas. Highly expressed in fetal tissue.
Database Links

HGNC: 12003

OMIM: 601990

KEGG: hsa:7161

STRING: 9606.ENSP00000367545

UniGene: Hs.192132

Pathway Hippo signaling pathway
p53 signaling pathway
Neurotrophin signaling pathway

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