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| Product Type | Recombinant Protein |
| Uniprot No. | Q9H9S0 |
| Abbreviation | NANOG |
| Species | Homo sapiens (Human) |
| Protocol |
Protocol may be improved. Please feel free to contact CUSABIO product specialist to obtain the latest version.
|
| Gene Names | NANOG |
| Protein Names | Recommended name: Homeobox protein NANOG Alternative name(s): Homeobox transcription factor Nanog Short name= hNanog |
| Storage | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. |
| Notes | Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week. |
| HGNC | 20857 |
| RGD | 1303178 |
| MGI | 1919200 |
| Function | Transcription regulator involved in inner cell mass and embryonic stem (ES) cells proliferation and self-renewal. Imposes pluripotency on ES cells and prevents their differentiation towards extraembryonic endoderm and trophectoderm lineages. Blocks bone morphogenetic protein-induced mesoderm differentiation of ES cells by physically interacting with SMAD1 and interfering with the recruitment of coactivators to the active SMAD transcriptional complexes. Acts as a transcriptional activator or repressor. Binds optimally to the DNA consensus sequence 5'-TAAT[GT][GT]-3' or 5'-[CG][GA][CG]C[GC]ATTAN[GC]-3'. Binds to the POU5F1/OCT4 promoter |
| Subcellular Location | Nucleus |
| Protein Families | Nanog homeobox family |
| Tissue Specificity | Expressed in testicular carcinoma and derived germ cell tumors (at protein level). Expressed in fetal gonads, ovary and testis. Also expressed in ovary teratocarcinoma cell line and testicular embryonic carcinoma. Not expressed in many somatic organs and |
| Database Links |
HGNC: 20857 OMIM: 607937 KEGG: hsa:79923 STRING: 9606.ENSP00000229307 UniGene: Hs.635882 |
| Pathway | Signaling pathways regulating pluripotency of stem cells |
| Product Name | Recombinant Human Homeobox protein NANOG(NANOG),Baculovirus |
| Code | CSB-BP888008HU |
| Size | Pls inquiry other sizes |
| Source | Baculovirus |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV |
| Expression Region | 1-305 |
| Protein Description | full length protein |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Product Name | Recombinant Human Homeobox protein NANOG(NANOG),Mammalian cell |
| Code | CSB-MP888008HU |
| Size | Pls inquiry other sizes |
| Source | Mammalian cell |
| Purity | >85% (SDS-PAGE) |
| Tag Info | The following tags are available. N-terminal His-tagged and C-terminal Myc-tagged N-terminal His-tagged Tag-Free The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
|
| Sequence | MSVDPACPQS LPCFEASDCK ESSPMPVICG PEENYPSLQM SSAEMPHTET VSPLPSSMDL LIQDSPDSST SPKGKQPTSA EKSVAKKEDK VPVKKQKTRT VFSSTQLCVL NDRFQRQKYL SLQQMQELSN ILNLSYKQVK TWFQNQRMKS KRWQKNNWPK NSNGVTQKAS APTYPSLYSS YHQGCLVNPT GNLPMWSNQT WNNSTWSNQT QNIQSWSNHS WNTQTWCTQS WNNQAWNSPF YNCGEESLQS CMQFQPNSPA SDLEAALEAA GEGLNVIQQT TRYFSTPQTM DLFLNYSMNM QPEDV |
| Expression Region | 1-305 |
| Protein Description | full length protein |
| Storage Buffer | Tris-based buffer,50% glycerol |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
NANOG Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA015424GA01HU | NANOG Antibody | Human | ELISA,WB,IF |
NANOG Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-MA888008A0m | NANOG Monoclonal Antibody | Human, Mouse, Rat | ELISA, WB, ICC, IF, FC |
| CSB-PA888008LA01HU | NANOG Antibody | Human | ELISA, WB, IHC |
| CSB-PA888008LC01HU | NANOG Antibody, FITC conjugated | Human | ELISA |
| CSB-PA888008LB01HU | NANOG Antibody, HRP conjugated | Human | ELISA |
| CSB-PA888008LD01HU | NANOG Antibody, Biotin conjugated | Human | ELISA |
NANOG Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-EP888008HU | Recombinant Human Homeobox protein NANOG(NANOG) | E.coli |
| CSB-YP888008HU | Recombinant Human Homeobox protein NANOG(NANOG) | Yeast |
| CSB-EP888008HUb1 | Recombinant Human Homeobox protein NANOG(NANOG) | E.coli |
NANOG ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-EL015424HU | Human Homeobox protein NANOG(NANOG) ELISA kit | serum, plasma, tissue homogenates, cell lysates | 6.25 pg/mL |
Recombinant Mpuse T-cell surface glycoprotein CD3 epsilon chain(Cd3e),partial
Express system: Yeast
Species: Mus musculus (Mouse)
Recombinant Human Casein kinase I isoform epsilon(CSNK1E)
Express system: E.coli
Species: Homo sapiens (Human)
Recombinant Mouse Glutaminyl-peptide cyclotransferase(Qpct)
Express system: E.coli
Species: Mus musculus (Mouse)
Recombinant Human Telomerase reverse transcriptase(TERT),partial
Express system: E.coli
Species: Homo sapiens (Human)
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