Recombinant Human Interferon alpha/beta receptor 1(IFNAR1),partial,Baculovirus

Code CSB-BP011046HU
Product Type Recombinant Protein
Size Pls inquiry other sizes
Uniprot No. P17181
Storage The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
Storage Buffer Tris-based buffer,50% glycerol
Species Homo sapiens (Human)
Purity >85% (SDS-PAGE)
Source Baculovirus
Gene Names IFNAR1
Protein Names Recommended name: Interferon alpha/beta receptor 1 Short name= IFN-R-1 Short name= IFN-alpha/beta receptor 1 Alternative name(s): Cytokine receptor class-II member 1 Cytokine receptor family 2 member 1 Short name= CRF2-1
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Product Info The following tags are available.
N-terminal His-tagged and C-terminal Myc-tagged
N-terminal His-tagged
The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
Protein Description Partial
Target Details This protein is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.
HGNC 5432
RGD 1305399
MGI 107658
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Function Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1
Subcellular Location Isoform 1: Cell membrane, Single-pass type I membrane protein, Late endosome, Lysosome
Protein Families Type II cytokine receptor family
Tissue Specificity IFN receptors are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resi
Database Links

HGNC: 5432

OMIM: 107450

KEGG: hsa:3454

STRING: 9606.ENSP00000270139

UniGene: Hs.529400

Pathway Jak-STAT signaling pathway
PI3K-Akt signaling pathway
Natural killer cell mediated cytotoxicity
NOD-like receptor signaling pathway
Osteoclast differentiation
Toll-like receptor signaling pathway

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