Code | CSB-RA297464A0HU |
Size | US$210 |
Order now | |
Image |
|
Have Questions? | Leave a Message or Start an on-line Chat |
Application | Recommended Dilution |
---|---|
IHC | 1:50-1:200 |
The development of the CCR2 recombinant monoclonal antibody is a complex and precise process that requires several steps. Initially, the CCR2 monoclonal antibody is harvested, and its gene sequence is analyzed. A vector containing the CCR2 monoclonal antibody gene is then constructed and transfected into a host cell line for culturing. A synthetic peptide derived from human CCR2 is utilized as an immunogen to synthesize the CCR2 monoclonal antibody. The CCR2 recombinant monoclonal antibody is then purified using affinity chromatography to ensure high purity. To verify its specificity, the antibody is assessed using ELISA and IHC assays to confirm its ability to target CCR2 effectively.
CCR2 is an important receptor protein that regulates the migration and activation of immune cells in response to inflammation and injury. It is involved in the recruitment of monocytes and macrophages to sites of inflammation and tissue damage as well as the regulation of immune cell activation and differentiation. CCR2-mediated signaling can promote the activation and differentiation of T cells and dendritic cells, leading to the initiation and maintenance of immune responses. Dysregulation of CCR2 can contribute to various diseases, including inflammation, autoimmune disorders, and cancer.
There are currently no reviews for this product.