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CUSABIO got the DNA sequence of the CD81 monoclonal antibody that was produced from the splenocytes generated by the human CD81 synthesized peptide immunization. The DNA sequence was cloned into the plasmid and then transfected into cell lines for in vitro expression. The product is the CD81 recombinant monoclonal antibody. It is a rabbit IgG antibody purified using the affinity-chromatography method. This CD81 antibody has been validated in ELISA, WB, IHC, and FC applications and reacts with the CD81 protein from human, mouse, and rat sources.
CD81 is an immune system regulator that regulates immunological synapse development, adhesion, motility, receptor clustering, and signaling, among other biological functions. CD81 forms a compound with CD19 and CD21 in B cells, lowering the activation threshold for B cell receptors. CD81 has been discovered as a component of the B lymphocyte receptor as well as a hepatitis C virus-host entry factor.
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