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The generation of the CLDN4 recombinant monoclonal antibody involved the integration of CLDN4 antibody genes into plasmid vectors. These engineered plasmid vectors were subsequently introduced into appropriate host cells using exogenous protein expression techniques to facilitate antibody production. Following this production phase, the CLDN4 recombinant monoclonal antibody underwent purification through affinity chromatography. Comprehensive validation was conducted to confirm the suitability of this CLDN4 recombinant monoclonal antibody for both ELISA and FC applications.
CLDN4 protein is a critical component of tight junctions in epithelial tissues. Its main function is to establish and maintain the integrity of epithelial barriers, regulate ion and molecule transport across these barriers, and contribute to cell polarity and differentiation. Proper CLDN4 function is essential for the normal physiological function of various organs and tissues.
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