Recombinant Human CD40 ligand(CD40LG)

Code CSB-CF004937HU
Product Type Transmembrane Protein
Size Pls inquiry other sizes
Uniprot No. P29965
Storage Buffer Lyophilized from Tris/PBS-based buffer, 6% Trehalose, pH 8.0
Species Homo sapiens (Human)
Sequence MIETYNQTSPRSAATGLPISMKIFMYLLTVFLITQMIGSALFAVYLHRRLDKIEDERNLHEDFVFMKTIQRCNTGERSLSLLNCEEIKSQFEGFVKDIMLNKEETKKENSFEMQKGDQNPQIAAHVISEASSKTTSVLQWAEKGYYTMSNNLVTLENGKQLTVKRQGLYYIYAQVTFCSNREASSQAPFIASLCLKSPGRFERILLRAANTHSSAKPCGQQSIHLGGVFELQPGASVFVNVTDPSQVSHGTGFTSFGLLKL
Source in vitro E.coli expression system
Gene Names CD40LG
Protein Names Recommended name: CD40 ligand Short name= CD40-L Alternative name(s): T-cell antigen Gp39 TNF-related activation protein Short name= TRAP Tumor necrosis factor ligand superfamily member 5 CD_antigen= CD154 Cleaved into the follow
Expression Region 1-261
Tag Info 10xHis-SUMO-tag
Protein Description full length protein
Storage Store at -20°C, for extended storage, conserve at -20°C or -80°C.
Notes Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
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Function Cytokine that binds to CD40/TNFRSF5
Involvement in disease Immunodeficiency with hyper-IgM, type 1 (HIGM1)
Subcellular Location Cell membrane, Single-pass type II membrane protein, Cell surface, SUBCELLULAR LOCATION: CD40 ligand, soluble form: Secreted
Protein Families Tumor necrosis factor family
Tissue Specificity Specifically expressed on activated CD4+ T-lymphocytes.
Database Links

HGNC: 11935

OMIM: 300386

KEGG: hsa:959

STRING: 9606.ENSP00000359663

UniGene: Hs.592244

Pathway NF-kappa B signaling pathway
T cell receptor signaling pathway

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