CD40LG Antibody

Datasheet
Code CSB-PA067336
Former Code(s) CSB-PA154273
Size US$299
Uniprot No. P29965
Image
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane: Mouse liver tissue, Primary antibody: CSB-PA067336(CD40LG Antibody) at dilution 1/300, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1minute
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunogen Fusion protein of Human CD40LG
Raised in Rabbit
Species Reactivity Human,Mouse
Tested Applications ELISA,WB;ELISA:1:1000-1:2000,WB:1:200-1:1000
Relevance The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias CD40 ligand
Immunogen Species Homo sapiens (Human)
Target Names CD40LG
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Cytokine that binds to CD40/TNFRSF5
Involvement in disease Immunodeficiency with hyper-IgM, type 1 (HIGM1)
Subcellular Location Cell membrane, Single-pass type II membrane protein, Cell surface, SUBCELLULAR LOCATION: CD40 ligand, soluble form: Secreted
Protein Families Tumor necrosis factor family
Tissue Specificity Specifically expressed on activated CD4+ T-lymphocytes.
Database Links

HGNC: 11935

OMIM: 300386

KEGG: hsa:959

STRING: 9606.ENSP00000359663

UniGene: Hs.592244

Pathway NF-kappa B signaling pathway
T cell receptor signaling pathway

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