Biological News - Cusabio


Scientists identified a genetic cause of pachygyria
Scientists identified a genetic cause of pachygyriaA new research has identified a mutation in a gene called CTNNA2 that is responsible for pachygyria, a severe developmental brain disorder. The finding provides insights into molecular processes that control brain develo...
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Zc3h8 overexpression contributes to breast cancer
Zc3h8 overexpression contributes to breast cancerResearchers from Villanova University have found a gene implicated in breast cancer. The discovery would extend our understanding of the life-threatening disease. Prof. Janice Knepper at Villanova University has been ...
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Scientists find a way to make paralyzed mice walk again!
Scientists find a way to make paralyzed mice walk again!Every year, a number of people become paralyzed for various reasons such as a traffic accident. They have an eager desire of regaining the ability of movement. Now, scientists have found a way to make paraly...
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A new class of drugs effectively fights cancer without causing side effects
A new class of drugs effectively fights cancer without causing side effectsDescribed in Nature, a study has found a new class of anti-cancer drugs that puts cancer cells to 'sleep'. Unlike conventional chemotherapy and radiotherapy, these new drugs do not cause DNA damage and related side effec...
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A well-studied protein may overcome cocaine relapse
A well-studied protein may overcome cocaine relapseIt's extremely hard to overcome drug addiction. Scientists in this field have been long seeking for ways to prevent drug relapse. Now, a new study published in Addiction Biology has shown that a common prote...
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Polycystic ovary syndrome may increase the rates of autism in your children
Polycystic ovary syndrome may increase the rates of autism in your childrenResearchers from the University of Cambridge and Yale University School of Public Health have shown that polycystic ovary syndrome, a hormonal condition that occurs in approximately 5 to 10 percent of women of reproducti...
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Targeting YAP unleashes immune system to attack cancer
Targeting YAP unleashes immune system to attack cancerA new research, carried out by an international team, has unraveled that blocking a known protein may unleash the immune system to attack cancer and improve the efficacy of immunotherapies. Regulatory T cell...
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Novel peptide-based vaccine shows strong protection against influenza
Novel peptide-based vaccine shows strong protection against influenzaThe flu, or called influenza, is a widespread, highly contagious disease caused by influenza viruses. Despite the presence of flu vaccines, about 291,000 to 646,000 people die of the disease annually, according to the Wo...
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Researchers find a non-human primate model of Batten disease
Researchers find a non-human primate model of Batten diseaseBatten disease, also known as neuronal ceroid lipofuscinosis (NCL), is an extremely rare and fatal neurodegenerative disorder that impairs many basic bodily functions.  Affected children often die of the disease at ...
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Study reveals IL-12 confers protection against childhood malaria
Study reveals IL-12 confers protection against childhood malariaA new study led by Curtin University has demonstrated that a protein called IL-12 helps combat malaria in newborns. Malaria is a serious disease caused by parasites that are mainly transmitted by mosquitoes....
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LRRK2 overactivity is a cause of Parkinson's disease
LRRK2 overactivity is a cause of Parkinson's diseaseNew research has shown that a gene previously shown to associate with a small proportion of Parkinson's disease (PD) cases may actually account for most cases of the disease. PD is a disease that primarily o...
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Blood test predicts whether patients with prostate cancer would benefit from ARS inhibitors
Blood test predicts whether patients with prostate cancer would benefit from ARS inhibitors Scientists have shown that a blood test is capable of predicting treatment response in suffers of advanced prostate cancer, according to a new study (Assessment of the Validity of Nuclear-Localized Androgen Receptor Spli...
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Physical exercise increases the likelihood of successful aging
Physical exercise increases the likelihood of successful agingHave you ever think about what it would be when you get older? When you get old, you don't seem to have to work and have lots of free time to do what you want to do. Sounds pretty good, doesn't it? But aging often means ...
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Restoration of mitochondrial function diminishes aging symptoms in mice
Restoration of mitochondrial function diminishes aging symptoms in miceTurning on a mutated gene responsible for mitochondrial dysfunction led to wrinkled skin and hair loss in mice, and these aging symptoms were reversed by turning off this gene. This is the finding of a mouse study by car...
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Allergic reactions may confer protection against skin cancer
Allergic reactions may confer protection against skin cancerMany people experience allergic reactions, ranging from mild to severe. For example, mango allergies commonly occur on the skin around the mouth, which trigger itching and burning; peanut allergies can trigger skin rashe...
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Why do men recover faster from the flu than women?
Why do men recover faster from the flu than women?There are differences in physiology between women and man. One example is that men generally recover faster from the flu than women. Now, a new study provides insights into this sex difference. Described in ...
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A particular muscarinic receptor could be targeted to improve multiple sclerosis
A particular muscarinic receptor could be targeted to improve multiple sclerosisA new research has identified a drug target for multiple sclerosis (MS), the most widespread disabling neurological condition among young adults. Published in The Journal of Neuroscience, the research (Muscarinic rece...
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Metabolites of omega-3 fatty acids exhibit anti-tumor effect in bone cancer
Metabolites of omega-3 fatty acids exhibit anti-tumor effect in bone cancerIn a paper (Antitumorigenic Properties of Omega-3 Endocannabinoid Epoxides) published in the Journal of Medicinal Chemistry, researchers from the University of Illinois report that products of omega-3 fatty acid metaboli...
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Antisense oligonucleotides may be an efficacious therapy for ALS
Antisense oligonucleotides may be an efficacious therapy for ALSAmyotrophic lateral sclerosis (ALS) is a debilitating disease that affects neurons in the central nervous system, impairing the function of voluntary muscles. Over time, patients with ALS become less able to chew, walk, ...
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Fat appears to be the only macronutrient that causes obesity
Fat appears to be the only macronutrient that causes obesityObesity is an increasingly important problem worldwide. Numerous efforts have been made to uncover the mechanisms underlying energy intake, storage, and expenditure in the body. Such studies would help develop more effec...
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An explanation for nonresponse to checkpoint inhibitors in some cancer patients
An explanation for nonresponse to checkpoint inhibitors in some cancer patientsA research has uncovered that some tumor cells co-express two checkpoint proteins, and this co-expression may explain why checkpoint inhibitors fail to work in some cancer patients. Our bodies' immune system...
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Only some people can benefit from a Mediterranean diet
Only some people can benefit from a Mediterranean dietEating a Mediterranean diet is known to have many health benefits. Now a new study has provided novel evidence to support the health benefits of a Mediterranean diet. The study, carried out researchers at IRCCS Istituto ...
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Vitamin D may have no significant effects against brain disorders
Vitamin D may have no significant effects against brain disordersWhen it comes to vitamin D, many people know that it has a lot of health benefits, such as promoting the absorption of calcium. Recent studies have suggested that vitamin D has a neuroprotective role and tha...
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CD271 may serve as a diagnostic and prognostic marker for a subgroup of brain tumor
CD271 may serve as a diagnostic and prognostic marker for a subgroup of brain tumorA study, carried out researchers from the University of Manitoba, Ottawa Hospital Research Institute, Hospital for Sick Children, Kansas University Medical Center, and the  University of Calgary, has uncovered a dia...
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A breakthrough in HIV prevention
A breakthrough in HIV preventionA research published in The Lancet has demonstrated the great potential of new HIV-1 vaccine regimens to prevent HIV-1 infection. The research represents a breakthrough in HIV prevention but more investigation is require...
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Research finds a way to reverse pathology that causes dementia
Research finds a way to reverse pathology that causes dementiaYou may not be unfamiliar with the problem of population aging. Population aging is both a social problem and an economic problem. It refers to a process in which the median age in the population of a region is increasin...
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Solvents confer risk for multiple sclerosis
Solvents confer risk for multiple sclerosisExposure to solvents such as paint and varnish may increase the risk of developing a disabling disease of the central nervous system, especially when people carry risk genes. This is the discovery of a new study (Organic...
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CMV improves immunity in old mice, study finds
CMV improves immunity in old mice, study findsWhy are the elderly more likely to get infectious diseases compared with the young? The reason lies in our immune systems. As people age, the immune system becomes less effective in multiple ways. Firstly, the immune sys...
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C6orf106 identified as an inhibitor of antiviral response
C6orf106 identified as an inhibitor of antiviral responseCSIRO scientists in Australia have discovered that the C6orf106 gene (simply known as C6) inhibits the innate antiviral response. The discovery would have intriguing implications for antiviral immunity, autoimmune disord...
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TRAF7 variants linked to human development disorder
TRAF7 variants linked to human development disorderA new study has identified a link between mutations in the TRAF7 gene and a multisystem disorder. In addition, there might also be an association between TRAF7 and other diseases such as cancer and RASopathy. ...
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TWIK2 channel mediates inflammation, study finds
TWIK2 channel mediates inflammation, study findsA new study has identified a potential target for anti-inflammatory therapies. The study was carried out by scientists from the University of Illinois College of Medicine and St. Jude Children's Research Hospital, and it...
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Effect of ARID1A on transcription and tumorigenesis identified
Effect of ARID1A on transcription and tumorigenesis identifiedScientists from The Wistar Institute and the University of Pennsylvania have gained new insights into the role of the tumor suppressor ARID1A in transcription and tumorigenesis. Described in the journal Cell Reports, the...
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Two herpesviruses found to contribute to Alzheimer's disease
Two herpesviruses found to contribute to Alzheimer's diseaseA large number of diseases have been identified to affect humans. Progress in medicine has greatly improved the treatment of many diseases. For example, tuberculosis or TB once killed one out of every seven people in som...
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A potential way to treat diabetes
A potential way to treat diabetesA new study led by researchers from ETH Zurich and the University of Basel in Switzerland and Institut Universitaire de Technologie in France has shown that cells engineered to produce insulin control glucose levels in t...
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A commonly used pigment is linked to diabetes, study finds
A commonly used pigment is linked to diabetes, study findsTitanium dioxide (TiO2), a common white pigment used in everyday products, might contribute to the common metabolic disease diabetes, according to a new study (Association of Type 2 Diabetes with Submicron Titanium Dioxi...
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Novel gene targets for cancer metastasis
Novel gene targets for cancer metastasisCancer has always been a hot spot in the field of medical research. What makes cancer so difficult to treat? Cancer metastasis, which refers to the movement of cancer cells from their original location to other parts of ...
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Stress may result in autoimmune diseases
Stress may result in autoimmune diseasesA large body of evidence supports the influence of stress on human health. In a novel study described in the Journal of the American Medical Association, researchers headed by Dr. Huan Song of the University of Iceland r...
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Inhibition of AMPK might be a strategy for treating deadly brain cancer
Inhibition of AMPK might be a strategy for treating deadly brain cancerAMPK, an enzyme thought to be a tumor suppressor, may actually promote brain tumor growth. This is the discovery of a new study (AMP kinase promotes glioblastoma bioenergetics and tumor growth) published this week in the...
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Women staying up late may be at elevated risk of depression
Women staying up late may be at elevated risk of depressionThe health benefits of going to bed early at night and rising early in morning are emphasized now and then. Now a new study provides further evidence for this. Published in the Journal of Psychiatric R...
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Who are vulnerable to the flu?
Who are vulnerable to the flu?Influenza, more commonly known as the flu, is an extremely widespread disease that is caused by the flu virus. Populations with weakened immune systems, including children and the elderly, are vulnerable to the flu, part...
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Bacterial composition in the vagina may influence the risk of cervical cancer
Bacterial composition in the vagina may influence the risk of cervical cancerIt has been known for a while that long-term infection with HPV, especially with high-risk strains, may increase a woman's chance of developing cervical cancer, the second most common female-specific cancer after breast ...
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Does hunger make you angry?
Does hunger make you angry?Do you know the meaning of the word 'hangry'? It's blameless if you don't know because it was only recently that the Oxford Dictionary included this word. This word is a combination of two words, 'hunger' and 'anger', an...
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Zileuton improves tauopathy in mice
Zileuton improves tauopathy in miceInsufficient knowledge of mechanisms underlying dementia has hindered the development of effective therapies. A recent study provides new clues to the disease and may inform new treatments. The study, carried out by Temp...
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Study brings hope for patients with solid tumors
Study brings hope for patients with solid tumorsOur bodies have an immune system to prevent or fight against illnesses and infections. The immune system is critical for us to keep health. Individuals with a weakened immune system are more susceptible to illnesses and ...
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A natural antibody prevents atherosclerosis in mice
A natural antibody prevents atherosclerosis in micePhospholipids, which are a class of lipids, are the primary building blocks of cellular membranes and membranes surrounding organelles. They possess multiple functions, such as forming permeability barrier, providing a s...
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Type 1 diabetes leads to cognitive decline in the long-term
Type 1 diabetes leads to cognitive decline in the long-termDiabetes, cancer, autoimmune diseases, and many other complex conditions have increasingly become the focus of attention. Some diseases are referred to as 'complex conditions' because their etiology involves various fact...
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The culprit of brain tumor identified
The culprit of brain tumor identifiedA research study has identified the culprit of the most frequent primary brain tumor, glioblastoma multiforme. Carried out by researchers from Virginia Commonwealth University (VCU) and the University of California, the ...
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People with monogenic obesity would benefit from an appetite-controlling drug
People with monogenic obesity would benefit from an appetite-controlling drugAt a very young age, some people already become overweight or obese. In addition to lifestyle factors such as high-calorie diets and lack of physical activities, an individual’s genetic makeup also affects the risk of ...
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A mechanism by which APOE4 confers risk to Alzheimer's
A mechanism by which APOE4 confers risk to Alzheimer'sIn humans, there are different versions of the APOE gene, including APOE2, APOE3, and APOE4. Everyone has two copies of it, meaning that you may have E2/E2, E2/E3, E2/E4, E3/E3, E3/E4, or E4/E4. It has been established t...
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Triclosan found to negatively affect colonic inflammation
Triclosan found to negatively affect colonic inflammationA team consisting of scientists at the University of Massachusetts, the University of Wisconsin-Madison, University of California, Harvard Medical School, Northwestern University in the USA, Xi’an Jiaotong University, ...
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