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Structural analysis sheds light on how antibodies recognize a critical protein in malaria parasite
Structural analysis sheds light on how antibodies recognize a critical protein in malaria parasiteMalaria, one of the leading cause of death on our planet, is a preventable illness caused by parasites called plasmodia. To develop effective vaccines, a deep understanding of the parasite-host interactions is essential....
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Some women may be naturally protected against Zika virus
Some women may be naturally protected against Zika virusPregnant mothers and their unborn babies are prone to viral infections. Zika virus is one such threat that has received widespread concern in recent years. In most cases (about 80%), Zika infection is asymptomatic, meani...
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Novel approach to combating triple-negative breast cancer
Novel approach to combating triple-negative breast cancerTriple-negative breast cancer, an aggressive subtype of breast cancer, makes up about 15% of all breast cancer cases. A triple-negative breast cancer diagnosis means that the tumor is clinically negative for expression o...
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Cell therapy based on blood stem cells may provide a cure for type 1 diabetes
Cell therapy based on blood stem cells may provide a cure for type 1 diabetes Scientists have developed a cell therapy with the potential to cure type 1 diabetes (T1D) in mice. Because the cell therapy is based on autotransplantation, it will cause no serious side effects. Described i...
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A drug candidate holds promise in treating autism
A drug candidate holds promise in treating autismAutism spectrum disorder (ASD), or simply known as autism, is a large group of neurodevelopmental disorders with high heritability. It is characterized by disturbances in social behavior and communication. A recently ide...
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A double-stranded RNA successfully prevents liver cancer in mice
A double-stranded RNA successfully prevents liver cancer in miceScientists from the University of California in the USA and Fudan University in China have found a preventive strategy for liver cancer, one of the main killers in humans. The discovery is significant, especially for tho...
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Resistin and related molecules may provide new therapies for sepsis
Resistin and related molecules may provide new therapies for sepsisResearchers from the University of California and the University of Pennsylvania have demonstrated in mice that a human protein provides protection against a life-threatening condition known as "sepsis". Sep...
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Lack of the protein ankyrin-B contributes to obesity
Lack of the protein ankyrin-B contributes to obesityWhat is the chief culprit of obesity? There are various possible answers, such as a high fat, high cholesterol diet, and a sedentary lifestyle. However, things are not so simple. In fact, some individuals are more prone ...
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New therapeutic target for treating AML
New therapeutic target for treating AMLAcute myeloid leukemia (AML) is a fast-growing cancer of the myeloid line of blood cells. Most AML patients who achieve complete remission after initial treatment will eventually relapse. That's what makes the disease so...
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Therapeutics that enhance SORLA might combat Alzheimer's disease
Therapeutics that enhance SORLA might combat Alzheimer's diseaseAlzheimer's disease (AD) is the most common irreversible cause of dementia, accounting for 50-70% of all dementia cases. Of the various genetic risk factors linked to AD, apolipoprotein E (ApoE) is the most prevalent one...
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Structure analysis of viral protein provides clues to how RVFV infects a cell
Structure analysis of viral protein provides clues to how RVFV infects a cellViral infections are a serious threat to public health and livestock husbandry. Some viruses can be easily and efficiently transmitted to humans and/or animals by mosquitos. A recent study will help develop novel weapons...
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Eating mushrooms makes you younger?
Eating mushrooms makes you younger?We are told that eating mushrooms is good for our health. Now, a new study provides evidence to this. Researchers, including Michael Kalaras, John Richie, Ana Calcagnotto, and Robert Beelman from the Pennsyl...
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Promising approach to suppress cancer growth by restricting glucose consumption
Promising approach to suppress cancer growth by restricting glucose consumptionScientists from the University of Colorado Anschutz Medical Campus (CU Anschutz) have found an approach to suppress cancer growth by restricting glucose consumption. Oxygen and nutrients like glucose are del...
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Manipulation of RNA splicing causes old cells to become young
Manipulation of RNA splicing causes old cells to become youngA group composed of scientists from the University of Exeter, the University of Brighton, and the University of Oxford, has shown that manipulation of splicing factors -- proteins involved in the removal of introns from ...
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Study provides potential therapies for an inherited form of muscular dystrophy
Study provides potential therapies for an inherited form of muscular dystrophyBy screening existing compounds and experimental drugs, a team of researchers from Fred Hutchinson Cancer Research Center, Saint Louis University, the University of Rochester Medical Center, and Leiden University Medical...
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MicroRNA could modulate the development of nicotine dependence
MicroRNA could modulate the development of nicotine dependenceA new research has unveiled a previously unrecognized role for microRNA in nicotine dependence. The research would help understand why it's so difficult for people to stop smoking. A paper describing the res...
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Possible approach discovered for treating fragile X Syndrome
Possible approach discovered for treating fragile X SyndromeThe chromatin binding protein, Brd4, could be a drug target for a common form of inherited intellectual disability, according to a study published in the 17 August 2017 issue of the journal Cell. The study w...
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New study offers a potential way to overcome cancer resistance to treatment
New study offers a potential way to overcome cancer resistance to treatmentResearchers from the University of California San Francisco (UCSF) have shown that the enzyme GPX4 could be targeted to prevent acquired drug resistance. The discovery would improve cancer treatment in the future. ...
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