EGFR and Its Application in Cancer Therapy1. Basic Information of EGFR Protein 2. The Structure of EGFR Protein 3. EGFR Protein Signaling Pathway 4. EGFR and Tumor 5. EGFR Antibody D...
Detailed information

Information You Must Know about KCNN4Calcium-activated potassium channels (KCa) belong to the superfamily of potassium channels. Calcium-activated potassium channels play an important role in regulating vascular membrane potential and tension, as well as re...
Detailed information

Two Types of Macrophages: M1 and M2 MacrophagesMacrophages are a common phagocytic cell and a member of immune cells. It is a white blood cell located in a tissue derived from monocytes. It is characterized by plasticity and versatility. It plays an important role in...
Detailed information

Surface Markers That Help You Identify LymphocytesLymphocytes are the smallest white blood cells. It is an immune-recognition cell line produced by lymphoid organs. According to their migration, surface makers and biological functions, they can be divided into thre...
Detailed information

Cell Differentiation Determines the Fate of CellsCell differentiation is the process where a cell changes from one type to many different types. In the process of cell differentiation, there are differences in morphological structure and physiological function. All org...
Detailed information

CAR-T Cell Therapy- An Useful Treatment To CancerGenerally speaking, the foundations of cancer treatment were surgery, chemotherapy, and radiation therapy. But over the past several years, immunotherapy, one type of therapies enlists and strengthens the power of a pati...
Detailed information

LPS/TLR4 Signal Transduction PathwayIn 1980, Nüsslein-Volhard et al. discovered a gene that determines the dorsal-ventral differentiation in the development of Drosophila embryos and named it Toll [1] [2]. Later, similar homologous receptors were found in...
Detailed information

What Are the Effects of Abnormalities in the ALK GeneAnaplastic lymphoma kinase (ALK) is a transmembrane receptor tyrosine kinase of the insulin receptor superfamily. It is highly homologous with leukocyte tyrosine kinase [1]. ALK plays a major role in the develop...
Detailed information

These Tumor Databases You Have To KnowCurrently, malignant tumor has become one of the causes of death. The incidence of cancer is increasing globally and the age of onset is getting younger. In 2019, the latest data published by A Cancer Journ...
Detailed information

Toll-like Receptors--The Eye of Innate ImmunityToll-like receptors (TLRs) is a type I transmembrane protein, can identify different pathogen associated molecular patterns (PAMPs), belongs to the surface of the pattern recognition receptors (PRRs). Toll-like receptors...
Detailed information