Differentiation of Th17 CellsCD4+ T cells are classified into subgroups such as Th1, Th2, and regulatory T cells (Treg) depending on cell differentiation and functional properties. Recent studies have found that a new CD4+ T effector T-helper 17 cel...
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Tools You Need For Fundamental ResearchFundamental research, also called pure research or basic research, advances fundamental knowledge about the world. It aims to improve scientific theories for improved understanding or prediction of natural or other pheno...
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What Powerful Model Organism DatabasesModel organism, a non-human species, refers to a series of selected organisms, which used to reveal a life phenomenon with universal laws by biologists. Due to the conservation of biological evolution, information about ...
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How do Th1 and Th2 Cells Differentiate?Depending on the cytokines they synthesize and secrete, CD4+ helper T cells (Th) can be divided into two subgroups, type I helper T lymphocytes (Thl) and type II helper T cells (Th2) [1]. Both types of cells are differen...
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TCGA Database- A Good Partner of ResearchersThe Cancer Genome Atlas (TCGA) is a project collaboratively monitored by the National Cancer Institute (NCI) and the National Human Genome Research Institute in the United States (NHGRI) that has generated comprehensive,...
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Unraveling the Dynamic World of Histone Modifications: Implications in Gene Regulation and Disease PathogenesisHistone modification is a captivating and intricate field of epigenetics that delves into the dynamic changes in chromatin structure. This remarkable process profoundly impacts gene expression, transcriptional regulation...
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Histone modification and CancerHistone modification is an epigenetic mechanism by which more than 100 different post-translational modifications may occur at the amino-terminal ends of the histone tails in nucleosomes. Such modifications contain methy...
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How to Measure Histone Modification?Currently, in the research of histone modification, the most frequent and important issue is how to measure histone modification. And compared with the analysis of DNA methylomes, the implementation of epigenomic technol...
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How Does Histone Modification Affect Gene Expression?As mentioned in the article entitled "What a Powerful Artifact of DNA Compression - Histone", a histone modification is a series of post-translational modification (PTM) to histone proteins including methylation, phospho...
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Epigenetic Histone Modifications PathwayDisease and disorder research has been conducted in relation to the histone modifications pathway and malignant neoplasms, carcinogenesis, cell transformation, neoplastic, carcinoma. The histone modifications pathway has...
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