How to Choose the Right Secondary Antibody?
How to Choose the Right Secondary Antibody?Generally speaking, a secondary antibody binds with a primary antibody that is directly attached to the target antigen. In this words, we mention two groups of antibody, one is primary antibody and another is secondary a...
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Knowledge about Transthyretin
Knowledge about TransthyretinTransthyretin (TTR) is also known as vitamin A binding protein, pre-albumin (PA), and thyroid-binding pre-albumin. It is a plasma transporter, mainly synthesized by the liver, that binds and transports thyroxine and reti...
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How to Choose the Loading Control Antibodies?
How to Choose the Loading Control Antibodies?Control antibodies, as the name means, are a series of internal control antibodies. Generally speaking, control antibody can be divided into two groups, including isotype control antibodies and loading control antibodies...
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Tag Antibodies, Your Good Partner in Protein Research
Tag Antibodies, Your Good Partner in Protein ResearchBefore introducing the tag antibody, let's briefly introduce the protein tag. A protein tag is a protein or polypeptide sequences genetically located at the C or N terminus of a recombinant protein, and the gene sequence...
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Differentiation of Th17 Cells
Differentiation of Th17 CellsCD4+ T cells are classified into subgroups such as Th1, Th2, and regulatory T cells (Treg) depending on cell differentiation and functional properties. Recent studies have found that a new CD4+ T effector T-helper 17 cel...
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How do Th1 and Th2 Cells Differentiate?
How do Th1 and Th2 Cells Differentiate?Depending on the cytokines they synthesize and secrete, CD4+ helper T cells (Th) can be divided into two subgroups, type I helper T lymphocytes (Thl) and type II helper T cells (Th2) [1]. Both types of cells are differen...
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Four Common Histone Modifications
Four Common Histone ModificationsA covalent post-translational modifications (PTM) to histone proteins, also known as histone modification, regulate gene expression by organizing the genome into active regions of euchromatin or inactive heterochromatin ...
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Histone modification and Cancer
Histone modification and CancerHistone modification is an epigenetic mechanism by which more than 100 different post-translational modifications may occur at the amino-terminal ends of the histone tails in nucleosomes. Such modifications contain methy...
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How to Measure Histone Modification?
How to Measure Histone Modification?Currently, in the research of histone modification, the most frequent and important issue is how to measure histone modification. And compared with the analysis of DNA methylomes, the implementation of epigenomic technol...
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How Does Histone Modification Affect Gene Expression?
How Does Histone Modification Affect Gene Expression?As mentioned in the article entitled "What a Powerful Artifact of DNA Compression - Histone", a histone modification is a series of post-translational modification (PTM) to histone proteins including methylation, phospho...
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