The Overview of Breast Cancer: Related Signaling Pathways, Therapeutic TargetsBreast cancer is a cancer that develops in the tissues of breasts. Symptoms of breast cancer usually include a lump in the breast, a change in breast shape, dimpling of the skin, fluid coming from the nipple, a newly inv...
Detailed information

The overview of Wnt signaling pathwayThe Wnt signaling pathways, highly conserved amongst various species, are a group of signal transduction pathways made of proteins that pass signals into a cell through cell surface receptors, and are essential in develo...
Detailed information

Crosstalk Between Autophagy and ApoptosisAutophagy, also known as type II programmed cell death, is involved in the development and progression of various diseases. There is a complex interaction between autophagy and apoptosis. For instance, they both can be a...
Detailed information

The Overview of Phage Display：Protocol, Classification, Application and FAQs1. What Is Phage Display Bacteriophage (phage) is a virus that infects and replicates within bacteria and archaea, for following the injection of their genome into its cytoplasm. Phage is composed of proteins th...
Detailed information

Production of Recombinant ProteinDue to their important functions, proteins are widely used for industrial, nutritional, and medical applications. An important way to generate large amounts of a specific protein is the recombinant DNA technology, which ...
Detailed information

How to Choose an Antibody for Scientific Research?Antibodies -- a special type of Y-shaped proteins -- are indispensable for scientific research. Western blot (WB), immunoprecipitation (IP), immunohistochemistry (IHC), immunofluorescence (IF), chromatin immunoprecipitat...
Detailed information

The Overview of AutophagyWhat is Autophagy? The Types of Autophagy Core Autophagy Proteins of The Autophagic Pathway Autophagy and Disease 1. What is Autophagy? Autophagy is...
Detailed information

Four Types of ELISAELISA, short for enzyme-linked immunosorbent assay, is a very mature method for the detection of various targets. One advantage of ELISA is that it's quick and simple to carry out, so it is often used for both diagnostic...
Detailed information

TWIK2 channel mediates inflammation, study findsNovel way to control inflammation A new study has identified a potential target for anti-inflammatory therapies. The study was carried out by scientists from the University of Illinois College of Medicine and St. Jude...
Detailed information

The Overview of Hippo Signaling Pathway1. What is Hippo Signaling Pathway? The Hippo signaling pathway, also known as the Salvador/Warts/Hippo (SWH) pathway, consists of a group of conserved kinases and controls organ size through the regulation of c...
Detailed information