The difference between primary antibody and secondary antibody
The difference between primary antibody and secondary antibodyWhat is the difference between a primary antibody and a secondary antibody? This is a frequently asked question by green hands in the laboratory. Here we will answer this question from five angles: binding capability, us...
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What Are the Best Methods for Protein Purification? A Practical Guide
What Are the Best Methods for Protein Purification? A Practical GuideProteins are essential biomolecules involved in various biological processes, making their isolation and purification crucial for numerous applications in research, biotechnology, and medicine. This article p...
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The Recently Emerged New Swine Influenza Virus -- G4 EA-H1N1
The Recently Emerged New Swine Influenza Virus -- G4 EA-H1N1A paper published in the scientific journal PNAS on June 29, 2020 reported that Chinese researchers have identified a new swine influenza virus with pandemic potential [1]. As soon as the news burst out, there was an imm...
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Nanobody, what a Powerful Novel Antibody!
Nanobody, what a Powerful Novel Antibody!As the COVID-19 outbreaks in the world, we urgently need safe and effective antiviral antibodies to as new drugs and treatment options for combating the new coronavirus (SARS-CoV-2). When it comes to therapeutic antibodi...
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TMPRSS2, an Activator for SARS-CoV-2 Invasion
TMPRSS2, an Activator for SARS-CoV-2 InvasionWith the COVID-19 spreads around the world, scientists have work hard to explore the mechanism of SARS-CoV-2 invasion. And there are many SARS-CoV-2-Host interactome targets which have been reported, such as ACE2, TMPRSS...
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CD147, a New Target of SARS-CoV-2 Invasion
CD147, a New Target of SARS-CoV-2 InvasionAs of March 25, 2020, SARS-CoV-2 (formally named 2019-nCoV) has raged in more than 40 countries and regions, with a cumulative diagnosis of more than 338,924 people worldwide, and nearly 15,568 deaths. Previously, many s...
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The Application of IHC in Pathological Diagnosis
The Application of IHC in Pathological DiagnosisImmunohistochemistry (IHC) is a commonly detection technique in clinical pathological diagnosis. Since the 1970s, immunohistochemical technology has been applied to pathological diagnosis, which has a huge impact on the ...
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ACE2, The Hottest Target of SARS-CoV-2 Invasion
ACE2, The Hottest Target of SARS-CoV-2 InvasionA novel coronavirus ( SARS-CoV-2) was identified in Wuhan, Hubei Province, China in December of 2019. The SARS-CoV-2 has resulted in thousands of cases of lethal disease in China, with additional patients being identifie...
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What You Have to Know about Cytokine Storm and Virus Infection
What You Have to Know about Cytokine Storm and Virus InfectionOn January 25, 2020, Prof Bin Cao's team published a research paper titled "Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China.". The paper revealed that the immune system of critical pati...
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What Should You Know about Exosomes?
What Should You Know about Exosomes?The exosomes are vesicles secreted by the living cells to the extracellular space, with a diameter of 30-150 nm and a density of 1.13-1.19 g/mL. Almost all types of cells in the human body produce exosomes, which are nea...
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