PIK3R1

The following PIK3R1 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

PIK3R1 Antibodies

PIK3R1 Antibodies for Homo sapiens (Human)

PIK3R1 Proteins

PIK3R1 Proteins for Homo sapiens (Human)

PIK3R1 Proteins for Mus musculus (Mouse)

PIK3R1 Proteins for Bos taurus (Bovine)

PIK3R1 Proteins for Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii)

PIK3R1 Proteins for Rattus norvegicus (Rat)

PIK3R1 Background

Phosphatidylinositol 3-kinase regulatory subunit alpha is a protein in humans that is encoded by PIK3R1 gene. PIK3R1 binds to activated (phosphorylated) protein-Tyr kinases, through its SH2 domain, and acts as an adapter, mediating the association of the p110 catalytic unit to the plasma membrane. PIK3R1 is necessary for the insulin-stimulated increase in glucose uptake and glycogen synthesis in insulin-sensitive tissues. Besides, it also plays an important role in signaling in response to FGFR1, FGFR2, FGFR3, FGFR4, KITLG/SCF, KIT, PDGFRA and PDGFRB.

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