| Homepage > Product > Recombinant human Glyceraldehyde-3-phosphate dehydrogenase protein |
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| Recombinant human Glyceraldehyde-3-phosphate dehydrogenase protein |
| Product Name £º |
Recombinant human Glyceraldehyde-3-phosphate dehydrogenase protein |
| Synonyms £º |
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| Catalog Number £º |
CSB-RP000254h |
| Relevance £º |
Has both glyceraldehyde-3-phosphate dehydrogenase and nitrosylase activities, thereby playing a role in glycolysis and nuclear functions, respectively. Participates in nuclear events including transcription, RNA transport, DNA replication and apoptosis. Nuclear functions are probably due to the nitrosylase activity that mediates cysteine S-nitrosylation of nuclear target proteins such as SIRT1, HDAC2 and PRKDC By similarity. Glyceraldehyde-3-phosphate dehydrogenase is a key enzyme in glycolysis that catalyzes the first step of the pathway by converting D-glyceraldehyde 3-phosphate (G3P) into 3-phospho-D-glyceroyl phosphate |
| Mol. Weight £º |
37 KD |
| Product Info £º |
GST tagged |
| Source £º |
E.coli derived |
| Purity £º |
95% |
| Image £º |
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| Storage Buffer £º |
6M guanidine hydrochloride, 20mM Tris |
| Storage £º |
Store at -20¡æ, for extended storage, conserve at -20¡æ or -80¡æ. |
| Notes £º |
Repeated freezing and thawing is not recommended. Store working aliquots at 4¡æ for up to one week. |
| AA sequence £º |
KVKVGVNGFGRIGRLVTRAAFNSGKVDIVAINDPFIDLNYMVYMFQYDSTHGKFHGTVKAENGKLVINGN
PITIFQERDPSKIKWGDAGAEYVVESTGVFTTMEKAGAHLQGGAKRVIISAPSADAPMFVMGVNHEKYDN
SLKIISNASCTTNCLAPLAKVIHDNFGIVEGLMTTVHAITATQKTVDGPSGKLWRDGRGALQNIIPASTG
AAKAVGKVIPELNGKLTGMAFRVPTANVSVVDLTCRLEKPAKYDDIKKVVKQASEGPLKGILGYTEHQVV
SSDFNSDTHSSTFDAGAGIALNDHFVKLISWYDNEFGYSNRVVDLMAHMASKE-
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| Referrences £º |
[1] "The glyceraldehyde 3 phosphate dehydrogenase gene family: structure of a human cDNA and of an X chromosome linked pseudogene; amazing complexity of the gene family in mouse."
Hanauer A., Mandel J.-L.
EMBO J. 3:2627-2633(1984) [PubMed: 6096136] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
[2] "The complete sequence of a full length cDNA for human liver glyceraldehyde-3-phosphate dehydrogenase: evidence for multiple mRNA species."
Arcari P., Martinelli R., Salvatore F.
Nucleic Acids Res. 12:9179-9189(1984) [PubMed: 6096821] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [MRNA].
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