CCL17 Antibody

Code CSB-PA856825ZA01DO
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Product Details

Full Product Name Rabbit anti-Canis familiaris (Dog) (Canis lupus familiaris) CCL17 Polyclonal antibody
Uniprot No. Q95N01
Target Names CCL17
Alternative Names C-C motif chemokine 17 (CC chemokine TARC) (Small-inducible cytokine A17) (Thymus and activation-regulated chemokine), CCL17, TARC
Raised in Rabbit
Species Reactivity Canis familiaris
Immunogen Recombinant Canis familiaris CCL17 protein
Immunogen Species Canis familiaris (Dog) (Canis lupus familiaris)
Conjugate Non-conjugate
Clonality Polyclonal
Isotype IgG
Purification Method Protein A/G
Concentration It differs from different batches. Please contact us to confirm it.
Buffer Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form Liquid
Tested Applications ELISA, WB (ensure identification of antigen)
Protocols ELISA Protocol
Troubleshooting and FAQs Antibody FAQs
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables ① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee ① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time Made-to-order (12-14 weeks)

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Target Background

(From Uniprot)
Chemotactic factor for t lymphocytes but not monocytes or granulocytes. May play a role in T-cell development in thymus and in trafficking and activation of mature T-cells. Binds to CCR4 and CCR8.
Gene References into Functions
  1. The present results suggest that TNF-alpha-induced CCL17 mRNA transcription in canine keratinocytes is positively regulated by p38 but negatively controlled by ERK. PMID: 20837364
  2. This study suggests that interferon-gamma may suppress granulocyte-macrophage colony stimulating factor production from canine keratinocytes, although further studies are required to confirm this. PMID: 20860556
  3. Inflammatory cytokines are important inducing factors for the production of CCL17 in the lesional skin of dogs with atopic dermatitis. atopic dermatitis. PMID: 20022349
Subcellular Location Secreted.
Protein Families Intercrine beta (chemokine CC) family
Tissue Specificity Expressed in thymus, spleen, lymph node, lung and heart.
Database Links

KEGG: cfa:403586

STRING: 9615.ENSCAFP00000012872

UniGene: Cfa.3450

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