Rac2 Antibody

Code CSB-PA344535XA01DLU
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Product Details

Full Product Name
Rabbit anti-Drosophila melanogaster (Fruit fly) Rac2 Polyclonal antibody
Uniprot No.
Target Names
Rac2
Alternative Names
Rac2 antibody; RacB antibody; CG8556 antibody; Ras-related protein Rac2 antibody
Raised in
Rabbit
Species Reactivity
Drosophila melanogaster (Fruit fly)
Immunogen
Recombinant Drosophila melanogaster (Fruit fly) Rac2 protein
Immunogen Species
Drosophila melanogaster (Fruit fly)
Conjugate
Non-conjugated
Clonality
Polyclonal
Isotype
IgG
Purification Method
Antigen Affinity Purified
Concentration
It differs from different batches. Please contact us to confirm it.
Buffer
Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4
Form
Liquid
Tested Applications
ELISA, WB (ensure identification of antigen)
Protocols
Troubleshooting and FAQs
Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Value-added Deliverables
① 200ug * antigen (positive control);
② 1ml * Pre-immune serum (negative control);
Quality Guarantee
① Antibody purity can be guaranteed above 90% by SDS-PAGE detection;
② ELISA titer can be guaranteed 1: 64,000;
③ WB validation with antigen can be guaranteed positive;
Lead Time
Made-to-order (14-16 weeks)

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Target Background

Function
Involved in integrin alpha-PS3/beta-nu-mediated phagocytosis of Gram-positive S.aureus by hemocytes.
Gene References into Functions
  1. Rac2 has a central role in regulating the Drosophila homeostatic system. PMID: 24488496
  2. Findings demonstrate that light-induced translocation of Arr2 occurs through a noncanonical rhodopsin/Rac2 pathway, which is distinct from the classical phototransduction cascade. PMID: 20176938
  3. From these results it appears that Rac2 is necessary for the larval cellular immune response. PMID: 16098145
  4. Rac2 is the main host factor whose function is inhibited by the GAP domain of the ExoS toxin PMID: 17903178
Subcellular Location
Cell membrane; Lipid-anchor; Cytoplasmic side.
Database Links

KEGG: dme:Dmel_CG8556

STRING: 7227.FBpp0305023

UniGene: Dm.3545

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