Recombinant Human Interleukin-18(IL18)

In Stock
Code CSB-AP004651HU
Product Type Interleukin
Size US$137
Uniprot No. Q14116
Lead Time 5-10 business days
Storage Buffer Lyophilized from a 0.2 μm filtered 1xPBS, pH 7.4
Alias Interleukin-18; Iboctadekin; Interferon gamma-inducing factor; IFN-gamma-inducing factor; Interleukin-1 gamma; IL-1 gamma;GIF; IL-18; IL-1g; IL1F4; MGC12320
Species Homo sapiens (Human)
Biological_Activity The ED50 as determined by its ability to induce NFKB reporter gene expression in HEK 293 cell line is typically 25.3 ng/mL.
Purity Greater than 95% as determined by SDS-PAGE.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence YFGKLESKLSVIRNLNDQVLFIDQGNRPLFEDMTDSDCRDNAPRTIFIISMYKDSQPRGMAVTISVKCEKISTLSCENKIISFKEMNPPDNIKDTKSDIIFFQRSVPGHDNKMQFESSSYEGYFLACEKERDLFKLILKKEDELGDRSIMFTVQNED
Research Area Immunology
Source Mammalian cell
Gene Names IL18
Expression Region 37-193aa
Tag Info C-terminal 6xHis-tagged
Mol. Weight 23.3 kDa
Protein Description Full Length of Mature Protein
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Function Augments natural killer cell activity in spleen cells and stimulates interferon gamma production in T-helper type I cells.
Subcellular Location Secreted
Protein Families IL-1 family
Database Links

HGNC: 5986

OMIM: 600953

KEGG: hsa:3606

STRING: 9606.ENSP00000280357

UniGene: Hs.83077

Pathway Inflammasome Signaling
NOD-like receptor signaling pathway

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