Recombinant Mouse Interleukin-11 protein(Il11) (Active)

In Stock
Code CSB-AP003361MO
Product Type Interleukin
Size US$112Purchase it in Cusabio online store
(only available for customers from the US)
Uniprot No. P47873
Lead Time 5-10 business days
Image
Storage Buffer 0.2 μm filtered PBS, pH 7.4 ,lyophilized
Alias IL-11
Species Mus musculus (Mouse)
Biological_Activity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using murine T11 cells is less than 2 ng/ml, corresponding to a specific activity of >5.0x105 IU/mg.
Purity >97% as determined by SDS-PAGE and HPLC.
Endotoxin Less than 1.0 EU/μg as determined by LAL method.
Sequence M+PGPPAGSPR VSSDPRADLD SAVLLTRSLL ADTRQLAAQM RDKFPADGDHSLDSLPTLAM SAGTLGSLQL PGVLTRLRVD LMSYLRHVQW LRRAGGPSLKTLEPELGALQ ARLERLLRRL QLLMSRLALP QAAPDQPVIP LGPPASAWGSIRAAHAILGG LHLTLDWAVR GLLLLKTRL
Research Area Immunology
Source E.coli
Gene Names Il11
Expression Region 22-199aa
Tag Info Tag-Free
Mol. Weight 19.1 kDa
Protein Description Full Length of Mature Protein
PubMed ID 8913282; 10026196; 22253262; 23948300
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Function Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production
Subcellular Location Secreted
Protein Families IL-6 superfamily
Database Links

KEGG: mmu:16156

STRING: 10090.ENSMUSP00000092492

UniGene: Mm.35814

Pathway Jak-STAT signaling pathway
Hematopoietic cell lineage

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