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| Code | CSB-PA763132 |
| Former Code(s) | CSB-PA956002 |
| Size | US$299 |
| Uniprot No. | P12644 |
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| Immunogen | Fusion protein of Human BMP4 |
| Raised in | Rabbit |
| Species Reactivity | Human,Mouse,Rat |
| Tested Applications | ELISA,WB,IHC;ELISA:1:2000-1:5000,WB:1:500-1:2000,IHC:1:25-1:100 |
| Relevance | The protein encoded by this gene is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily. The superfamily includes large families of growth and differentiation factors. Bone morphogenetic proteins were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. |
| Form | Liquid |
| Conjugate | Non-conjugated |
| Storage Buffer | -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
| Purification Method | Antigen affinity purification |
| Isotype | IgG |
| Alias | bone morphogenetic protein 4 |
| Immunogen Species | Homo sapiens (Human) |
| Protocols | ELISA Protocol Western Blotting(WB) Protocol Immunohistochemistry (IHC) Protocol |
| Target Names | BMP4 |
| Storage | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Still Have Questions? | Leave a Message or Start an on-line Chat |
| Function | Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction (By similarity). |
| Involvement in disease | Microphthalmia, syndromic, 6 (MCOPS6); Non-syndromic orofacial cleft 11 (OFC11) |
| Subcellular Location | Secreted, extracellular space, extracellular matrix |
| Protein Families | TGF-beta family |
| Tissue Specificity | Expressed in the lung and lower levels seen in the kidney. Present also in normal and neoplastic prostate tissues, and prostate cancer cell lines. |
| Database Links |
HGNC: 1071 OMIM: 112262 KEGG: hsa:652 STRING: 9606.ENSP00000245451 UniGene: Hs.68879 |
| Pathway |
Hippo signaling pathway
TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells |
BMP4 Antibodies for Human
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA05799A0Rb | BMP4 Antibody | Human, Mouse, Zebrafish | ELISA, WB, IHC |
BMP4 Antibodies for Homo sapiens (Human)
| Code | Product Name | Species Reactivity | Application |
|---|---|---|---|
| CSB-PA05799B0Rb | BMP4 Antibody, HRP conjugated | Human | ELISA |
| CSB-PA05799C0Rb | BMP4 Antibody, FITC conjugated | Human | ELISA |
| CSB-PA05799D0Rb | BMP4 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA002740GA01HU | BMP4 Antibody | Human,Mouse,Rat | ELISA,WB |
| CSB-PA212919 | BMP4 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
BMP4 Proteins for Homo sapiens (Human)
| Code | Product Name | Source |
|---|---|---|
| CSB-YP002740HU CSB-BP002740HU CSB-MP002740HU |
Recombinant Human Bone morphogenetic protein 4(BMP4) | Yeast Baculovirus Mammalian cell |
| CSB-EP002740HU | Recombinant Human Bone morphogenetic protein 4(BMP4) | E.coli |
BMP4 ELISA Kit for Homo sapiens (Human)
| Code | Product Name | Sample Types | Sensitivity |
|---|---|---|---|
| CSB-E17298h | Human bone morphogenetic protein 4 (BMP4) ELISA Kit | serum, plasma, cell culture supernates | 3.9 pg/mL |
2-hydroxyisobutyryl-HIST1H4A (K16) Antibody
Applications: ELISA, WB, IF, IP, ChIP
Species Reactivity: Human
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