BMP4

BMP4, also known as bone morphogenetic protein 4, is a member of the TGF-β superfamily that plays a crucial role in cell differentiation, development, and tumor growth. It functions by binding to BMP receptors, which then activate downstream signaling pathways involving Smads and MAP kinases. BMP4 is involved in various biological processes, including angiogenesis, osteogenesis, and chondrogenesis. Dysregulation of BMP4 has been linked to several diseases, such as cancer, cardiovascular diseases, and osteoporosis. In drug development, BMP4 inhibitors and activators are being investigated for their potential therapeutic effects in treating these diseases.

Validated Data

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

BMP4 Recombinant Monoclonal Antibody (CSB-RA257673A0HU)

Validated Data

Western Blot
Positive WB detected in: Hela whole cell lysate
All lanes: BMP4 antibody at 1:2000
Secondary
Goat polyclonal to rabbit IgG at 1/50000 dilution
Predicted band size: 47 kDa
Observed band size: 36-55 kDa

Immunofluorescence staining of Hela cell with CSB-RA257673A0HU at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was Alexa Fluor 508-congugated AffiniPure Goat Anti-Rabbit IgG(H+L).

Human bone morphogenetic protein 4 (BMP4) ELISA Kit (CSB-E17298h)

Validated Data

Code: CSB-E17298h

Size: 96T,5×96T,10×96T

Sensitivity: 3.9 pg/mL

Detection Range: 15.6 pg/mL-1000 pg/mL

These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.

The following BMP4 reagents supplied by CUSABIO are manufactured under a strict quality control system. Multiple applications have been validated and solid technical support is offered.

BMP4 Antibodies

BMP4 Proteins

BMP4 ELISA Kits

BMP4 Antibodies

BMP4 Antibodies for Homo sapiens (Human)

Code	Product Name	Species Reactivity	Application
CSB-PA05799A0Rb	BMP4 Antibody	Human, Mouse	ELISA, WB
CSB-PA05799B0Rb	BMP4 Antibody, HRP conjugated	Human	ELISA
CSB-PA002740GA01HU	BMP4 Antibody	Human,Mouse,Rat	ELISA,WB
CSB-PA763132	BMP4 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-PA212919	BMP4 Antibody	Human,Mouse,Rat	ELISA,WB,IHC
CSB-RA257673A0HU	BMP4 Recombinant Monoclonal Antibody	Human	ELISA, WB, IF

BMP4 Antibodies for Bos taurus (Bovine)

Code	Product Name	Species Reactivity	Application
CSB-PA002740ZA01BO	BMP4 Antibody	Bos taurus	ELISA, WB (ensure identification of antigen)

BMP4 Proteins

BMP4 Proteins for Homo sapiens (Human)

Code	Product Name	Source
CSB-YP002740HU CSB-BP002740HU CSB-MP002740HU CSB-EP002740HU-B	Recombinant Human Bone morphogenetic protein 4 (BMP4)	Yeast Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP002740HU	Recombinant Human Bone morphogenetic protein 4 (BMP4)	E.coli
CSB-EP002740HUa0	Recombinant Human Bone morphogenetic protein 4 (BMP4)	E.coli
CSB-EP002740HUc7	Recombinant Human Bone morphogenetic protein 4(BMP4)	E.coli

BMP4 Proteins for Mus musculus (Mouse)

Code	Product Name	Source
CSB-YP002740MO CSB-BP002740MO CSB-EP002740MO-B	Recombinant Mouse Bone morphogenetic protein 4 (Bmp4)	Yeast Baculovirus In Vivo Biotinylation in E.coli

BMP4 Proteins for Oryctolagus cuniculus (Rabbit)

Code	Product Name	Source
CSB-YP002740RB CSB-EP002740RB CSB-BP002740RB CSB-MP002740RB CSB-EP002740RB-B	Recombinant Rabbit Bone morphogenetic protein 4 (BMP4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BMP4 Proteins for Xenopus laevis (African clawed frog)

Code	Product Name	Source
CSB-YP002740XBE CSB-EP002740XBE CSB-BP002740XBE CSB-MP002740XBE CSB-EP002740XBE-B	Recombinant Xenopus laevis Bone morphogenetic protein 4 (bmp4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BMP4 Proteins for Gallus gallus (Chicken)

Code	Product Name	Source
CSB-YP002740CH CSB-EP002740CH CSB-BP002740CH CSB-MP002740CH CSB-EP002740CH-B	Recombinant Chicken Bone morphogenetic protein 4 (BMP4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BMP4 Proteins for Suncus murinus (Asian house shrew) (Musk shrew)

Code	Product Name	Source
CSB-YP002740FPS CSB-EP002740FPS CSB-BP002740FPS CSB-MP002740FPS CSB-EP002740FPS-B	Recombinant Suncus murinus Bone morphogenetic protein 4 (BMP4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BMP4 Proteins for Dama dama (Fallow deer) (Cervus dama)

Code	Product Name	Source
CSB-YP002740DIH CSB-EP002740DIH CSB-BP002740DIH CSB-MP002740DIH CSB-EP002740DIH-B	Recombinant Dama dama Bone morphogenetic protein 4 (BMP4)	Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli

BMP4 Proteins for Bos taurus (Bovine)

Code	Product Name	Source
CSB-BP002740BO CSB-MP002740BO CSB-EP002740BO-B	Recombinant Bovine Bone morphogenetic protein 4 (BMP4)	Baculovirus Mammalian cell In Vivo Biotinylation in E.coli
CSB-EP002740BO	Recombinant Bovine Bone morphogenetic protein 4 (BMP4)	E.coli