CCR6 Antibody

Datasheet
Code CSB-PA943255
Size US$299
Uniprot No. P51684
Image
  • The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using CSB-PA943255(CCR6 Antibody) at dilution 1/50, on the right is treated with synthetic peptide. (Original magnification: ×200)
  • Gel: 8%SDS-PAGE, Lysate: 40 μg, Lane 1-4: A431 cells, HepG2 cells, Raji cells, K562 cells, Primary antibody: CSB-PA943255(CCR6 Antibody) at dilution 1/966, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 minute
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Synthetic peptide of Human CCR6
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA,WB,IHC;ELISA:1:2000-1:10000,WB:1:1000-1:5000,IHC:1:50-1:200
Relevance This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The gene is preferentially expressed by immature dendritic cells and memory T cells. The ligand of this receptor is macrophage inflammatory protein 3 alpha (MIP-3 alpha). This receptor has been shown to be important for B-lineage maturation and antigen-driven B-cell differentiation, and it may regulate the migration and recruitment of dentritic and T cells during inflammatory and immunological responses. Alternatively spliced transcript variants that encode the same protein have been described for this gene.
Form Liquid
Conjugate Non-conjugated
Storage Buffer -20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification Method Antigen affinity purification
Isotype IgG
Alias chemokine (C-C motif) receptor 6
Immunogen Species Homo sapiens (Human)
Target Names CCR6
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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Function Receptor for the C-C type chemokine CCL20
Subcellular Location Cell membrane, Multi-pass membrane protein, Cell surface
Protein Families G-protein coupled receptor 1 family
Tissue Specificity Sperm. Mainly localized in the tail and in the postacrosomal region but is also found in the midpiece and basal region in a small percentage of sperm cells. Reduced levels found in the sperms of asthenozoospermia and leukocytospermia patients (at protein
Database Links

HGNC: 1607

OMIM: 601835

KEGG: hsa:1235

STRING: 9606.ENSP00000339393

UniGene: Hs.46468

Pathway Chemokine signaling pathway

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