CD14 Antibody

Code CSB-PA004879GA01HU
Product Type Purified Rabbit Anti human PolyClonal Antibody
Size US$685
Uniprot No. P08571
Protocols ELISA Protocol
Western Blotting(WB) Protocol
Immunohistochemistry (IHC) Protocol
Immunogen Human CD14
Raised in Rabbit
Species Reactivity Human
Tested Applications ELISA,WB,IHC
Storage Buffer PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method Antigen Affinity purified
Isotype IgG
Alias CD14 molecule;
Immunogen Species Homo sapiens (Human)
Target Names CD14
Storage Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Target Details CD14 is a surface protein preferentially expressed on monocytes/macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform.
HGNC 1628
RGD 620588
MGI 88318
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Function Coreceptor for bacterial lipopolysaccharide
Subcellular Location Cell membrane, Lipid-anchor, GPI-anchor, Secreted, Membrane raft, Golgi apparatus
Tissue Specificity Detected on macrophages (at protein level) (PubMed:1698311). Expressed strongly on the surface of monocytes and weakly on the surface of granulocytes; also expressed by most tissue macrophages.
Database Links

HGNC: 1628

OMIM: 158120

KEGG: hsa:929

STRING: 9606.ENSP00000304236

UniGene: Hs.163867

Pathway MAPK signaling pathway
NF-kappa B signaling pathway
Regulation of actin cytoskeleton
Hematopoietic cell lineage
Toll-like receptor signaling pathway

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